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Articles Published Processes
4/30/2020 3:27:13 PM | Browse: 842 | Download: 1682
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Received |
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2020-01-16 11:59 |
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Peer-Review Started |
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2020-01-16 12:01 |
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To Make the First Decision |
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Return for Revision |
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2020-03-27 19:19 |
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Revised |
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2020-04-08 09:27 |
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Second Decision |
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2020-04-20 12:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-04-20 17:41 |
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Articles in Press |
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2020-04-20 17:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-04-23 01:16 |
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Typeset the Manuscript |
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2020-04-29 08:30 |
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Publish the Manuscript Online |
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2020-04-30 15:27 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Central nervous system relapse in a pediatric anaplastic large cell lymphoma patient with CLTC/ALK translocation treated with alectinib: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing Yang, Jun Li, Wei-Yue Gu, Ling Jin, Yan-Long Duan, Shuang Huang, Meng Zhang, Xi-Si Wang, Yi Liu, Chun-Ju Zhou, Chao Gao, Hu-Yong Zheng and Yong-Hong Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hu-Yong Zheng, MD, Doctor, Doctor, Beijing Key Laboratory of Pediatric Hematology Oncology, National Discipline of Pediatrics, Ministry of Education, MOE Key Laboratory of Major Diseases in Children; Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children’s Health, No. 56 Nanli- shi Road, 100045 100045, China. zhenghuyong@vip.sina.com |
| Key Words |
Anaplastic; Lymphoma; Pediatric; CLTC/ALK; Central nervous system; Alectinib |
| Core Tip |
Both CLTC-anaplastic lymphoma kinase translocation and central nervous system (CNS) metastasis are very rare in anaplastic large cell lymphoma. This study reports a rare pediatric case of anaplastic large cell lymphoma with the CLTC-anaplastic lymphoma kinase fusion gene. The patient had an aggressive clinical course and underwent CNS relapse during treatment. The current patient sustained complete remission with chemotherapy and alectinib. Alectinib conferred significant and durable CNS effects in this patient. |
| Publish Date |
2020-04-30 15:27 |
| Citation |
Yang J, Li J, Gu WY, Jin L, Duan YL, Huang S, Zhang M, Wang XS, Liu Y, Zhou CJ, Gao C, Zheng HY, Zhang YH. Central nervous system relapse in a pediatric anaplastic large cell lymphoma patient with CLTC/ALK translocation treated with alectinib: A case report. World J Clin Cases 2020; 8(9): 1685-1692 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i9/1685.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i9.1685 |
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