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4/30/2020 3:27:13 PM | Browse: 714 | Download: 1274
Publication Name World Journal of Clinical Cases
Manuscript ID 54244
Country China
Received
2020-01-16 11:59
Peer-Review Started
2020-01-16 12:01
To Make the First Decision
Return for Revision
2020-03-27 19:19
Revised
2020-04-08 09:27
Second Decision
2020-04-20 12:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-04-20 17:41
Articles in Press
2020-04-20 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-04-23 01:16
Typeset the Manuscript
2020-04-29 08:30
Publish the Manuscript Online
2020-04-30 15:27
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Central nervous system relapse in a pediatric anaplastic large cell lymphoma patient with CLTC/ALK translocation treated with alectinib: A case report
Manuscript Source Unsolicited Manuscript
All Author List Jing Yang, Jun Li, Wei-Yue Gu, Ling Jin, Yan-Long Duan, Shuang Huang, Meng Zhang, Xi-Si Wang, Yi Liu, Chun-Ju Zhou, Chao Gao, Hu-Yong Zheng and Yong-Hong Zhang
ORCID
Author(s) ORCID Number
Jing Yang http://orcid.org/0000-0002-1455-4253
Jun Li http://orcid.org/0000-0001-7232-0036
Wei-Yue Gu http://orcid.org/0000-0002-7551-2006
Ling Jin http://orcid.org/0000-0001-7148-141X
Yan-Long Duan http://orcid.org/0000-0003-2048-6397
Shuang Huang http://orcid.org/0000-0002-7967-9743
Meng Zhang http://orcid.org/0000-0002-9695-5279
Xi-Si Wang http://orcid.org/0000-0002-0565-6530
Yi Liu http://orcid.org/0000-0002-7041-305X
Chun-Ju Zhou http://orcid.org/0000-0002-5664-3190
Chao Gao http://orcid.org/0000-0001-6652-5457
Hu-Yong Zheng http://orcid.org/0000-0002-6220-2789
Yong-Hong Zhang http://orcid.org/0000-0003-1960-3349
Funding Agency and Grant Number
Corresponding Author Hu-Yong Zheng, MD, Doctor, Beijing Key Laboratory of Pediatric Hematology Oncology, National Discipline of Pediatrics, Ministry of Education, MOE Key Laboratory of Major Diseases in Children; Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children’s Health, No. 56 Nanli- shi Road, 100045 100045, China. zhenghuyong@vip.sina.com
Key Words Anaplastic; Lymphoma; Pediatric; CLTC/ALK; Central nervous system; Alectinib
Core Tip Both CLTC-anaplastic lymphoma kinase translocation and central nervous system (CNS) metastasis are very rare in anaplastic large cell lymphoma. This study reports a rare pediatric case of anaplastic large cell lymphoma with the CLTC-anaplastic lymphoma kinase fusion gene. The patient had an aggressive clinical course and underwent CNS relapse during treatment. The current patient sustained complete remission with chemotherapy and alectinib. Alectinib conferred significant and durable CNS effects in this patient.
Publish Date 2020-04-30 15:27
Citation Yang J, Li J, Gu WY, Jin L, Duan YL, Huang S, Zhang M, Wang XS, Liu Y, Zhou CJ, Gao C, Zheng HY, Zhang YH. Central nervous system relapse in a pediatric anaplastic large cell lymphoma patient with CLTC/ALK translocation treated with alectinib: A case report. World J Clin Cases 2020; 8(9): 1685-1692
URL https://www.wjgnet.com/2307-8960/full/v8/i9/1685.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i9.1685
Full Article (PDF) WJCC-8-1685.pdf
Full Article (Word) WJCC-8-1685.docx
Manuscript File 54244-Review_WangTQ.docx
Answering Reviewers 54244-Answering reviewers.pdf
Audio Core Tip 54244-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 54244-Conflict-of-interest statement.pdf
Copyright License Agreement 54244-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54244-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 54244-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 54244-Language certificate.pdf
Peer-review Report 54244-Peer-review(s).pdf
Scientific Misconduct Check 54244-Scientific misconduct check.pdf
Scientific Editor Work List 54244-Scientific editor work list.pdf