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Articles Published Processes
7/26/2020 8:24:58 AM | Browse: 978 | Download: 1451
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Received |
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2020-02-18 12:05 |
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Peer-Review Started |
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2020-02-18 12:07 |
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To Make the First Decision |
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Return for Revision |
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2020-04-25 21:51 |
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Revised |
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2020-05-08 11:11 |
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Second Decision |
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2020-05-27 09:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-28 21:40 |
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Articles in Press |
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2020-05-28 21:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-06-04 10:38 |
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Typeset the Manuscript |
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2020-07-24 08:48 |
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Publish the Manuscript Online |
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2020-07-26 08:24 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Systematic Reviews |
Article Title |
Application and prospect of adipose stem cell transplantation in treating lymphedema
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Manuscript Source |
Invited Manuscript |
All Author List |
Zhu-Jun Li, Elan Yang, Yun-Zhu Li, Zheng-Yun Liang, Jiu-Zuo Huang, Nan-Ze Yu and Xiao Long |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Xiao Long, MD, PhD, Professor, Surgeon, Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences, No.1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. pumclongxiao@126.com |
Key Words |
Lymphedema; Adipose-derived stem cells; Animal model; Clinical trial; Vascular endothelial growth factor-C; Lymphangiogenesis |
Core Tip |
Lymphedema is a growing global health problem. Adipose-derived stem cells might serve as suitable seed cells for tissue engineering of lymphatic vessels in vitro and in vivo. Systematic search of publications on the application of adipose-derived stem cells in the treatment of lymphedema identified five animal studies and three clinical trials. All eight studies showed improvement of lymphedema after treatment with adipose-derived stem cells. Animal studies conducted with the acute lymphedema mouse model provided data for finding the proper dose and methods of administration. Clinical trials were conducted on breast cancer-related lymphedema patients and are important references for further application. |
Publish Date |
2020-07-26 08:24 |
Citation |
Li ZJ, Yang E, Li YZ, Liang ZY, Huang JZ, Yu NZ, Long X. Application and prospect of adipose stem cell transplantation in treating lymphedema. World J Stem Cells 2020; 12(7): 676-687 |
URL |
https://www.wjgnet.com/1948-0210/full/v12/i7/676.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v12.i7.676 |
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