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Articles Published Processes
7/7/2020 2:50:53 PM | Browse: 839 | Download: 2046
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Received |
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2020-02-03 10:43 |
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Peer-Review Started |
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2020-02-03 10:43 |
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To Make the First Decision |
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Return for Revision |
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2020-03-24 17:16 |
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Revised |
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2020-05-09 04:34 |
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Second Decision |
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2020-05-25 10:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-26 02:35 |
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Articles in Press |
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2020-05-26 02:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-06-09 02:32 |
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Typeset the Manuscript |
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2020-07-06 01:26 |
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Publish the Manuscript Online |
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2020-07-07 14:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
TBL1XR1 induces cell proliferation and inhibit cell apoptosis by the PI3K/AKT pathway in pancreatic ductal adenocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Feng Gu, Wei Fu, Hai-Xin Qian, Wen-Xiu Gu, Yang Zong, Qian Chen and Long Lu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jian-Feng Gu, MD, Doctor, Doctor, Department of General Surgery, Changshu No.1 People’s Hospital Affiliated to Soochow University, Yongjia Road 91, Changshu 215500, Jiangsu Province, China. jscsgjf@sina.cn |
| Key Words |
Pancreatic ductal adenocarcinoma; TBL1XR1; Proliferation; PI3K/AKT pathway; ; |
| Core Tip |
Transducin (β)-like 1 X-linked receptor 1 (TBL1XR1) has been linked to progression of virous human cancers. However, the function and role of TBL1XR1 is rarely known in pancreatic cancers. It is important to further reveal the effect and potential molecular mechanism of TBL1XR1 in pancreatic cancer. This study showed that TBL1XR1 promotes the Pancreatic ductal adenocarcinoma (PDAC) cells proliferation and inhibited PDAC cells apoptosis and might regulate PDAC cells proliferation and apoptosis by phosphatidylinositol 3-kinase/protein kinase B pathway. Therefore, TBL1XR1 might be a promising therapeutic marker for treating patients with advanced PDAC. |
| Publish Date |
2020-07-07 14:50 |
| Citation |
Gu JF, Fu W, Qian HX, Gu WX, Zong Y, Chen Q, Lu L. TBL1XR1 induces cell proliferation and inhibit cell apoptosis by the PI3K/AKT pathway in pancreatic ductal adenocarcinoma. World J Gastroenterol 2020; 26(25): 3586-3602 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i25/3586.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i25.3586 |
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