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7/15/2020 11:47:34 AM | Browse: 669 | Download: 1062
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 54558
Country/Territory Romania
Received
2020-02-04 16:51
Peer-Review Started
2020-02-04 16:51
To Make the First Decision
Return for Revision
2020-03-24 14:56
Revised
2020-04-06 11:01
Second Decision
2020-05-25 07:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-27 18:56
Articles in Press
2020-05-27 18:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-06-04 05:56
Typeset the Manuscript
2020-07-14 07:23
Publish the Manuscript Online
2020-07-15 11:47
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Maspin subcellular expression in wild-type and mutant TP53 gastric cancers
Manuscript Source Invited Manuscript
All Author List Simona Gurzu, Ioan Jung, Haruhiko Sugimura, Raluca Ioana Stefan-van Staden, Hidetaka Yamada, Hiroko Natsume, Yuji Iwashita, Rita Szodorai and Janos Szederjesi
ORCID
Author(s) ORCID Number
Simona Gurzu http://orcid.org/0000-0003-3968-5118
Ioan Jung http://orcid.org/0000-0001-6537-2807
Haruhiko Sugimura http://orcid.org/0000-0002-0779-3088
Raluca Ioana Stefan-van Staden http://orcid.org/0000-0001-8244-2483
Hidetaka Yamada http://orcid.org/0000-0001-5522-5264
Hiroko Natsume http://orcid.org/0000-0001-6895-4204
Yuji Iwashita http://orcid.org/0000-0002-9085-5429
Rita Szodorai http://orcid.org/0000-0001-8922-7823
Janos Szederjesi http://orcid.org/0000-0001-9359-6058
Funding Agency and Grant Number
Funding Agency Grant Number
Romanian National Authority for Scientific Research 20 PCCF/2018
Corresponding Author Simona Gurzu, MD, PhD, Chief Doctor, Director, Full Professor, Research Fellow, Research Scientist, Department of Pathology, University of Medicine, Pharmacy, Sciences and Technology, 38 Gheorghe Marinescu Street, Targu Mureș 530193, Mureș, Romania. simonagurzu@yahoo.com
Key Words p53; TP53 gene; Maspin; Gastric cancer; Carcinoma;
Core Tip In this paper we tried to emphasize the possible prognostic role of TP53 status, in gastric cancer, and its relation with Maspin protease. For the first time in literature, we have proved that TP53 gene mutations in exon 7 might induce knockdown Maspin but wild type p53 can partialy restore nuclear Maspin expression and decrease the metastatic potential of gastric adenocarcinoma cells.
Publish Date 2020-07-15 11:47
Citation Gurzu S, Jung I, Sugimura H, Stefan-van Staden RI, Yamada H, Natsume H, Iwashita Y, Szodorai R, Szederjesi J. Maspin subcellular expression in wild-type and mutant TP53 gastric cancers. World J Gastrointest Oncol 2020; 12(7): 741-755
URL https://www.wjgnet.com/1948-5204/full/v12/i7/741.htm
DOI https://dx.doi.org/10.4251/wjgo.v12.i7.741
Full Article (PDF) WJGO-12-741.pdf
Full Article (Word) WJGO-12-741.docx
Manuscript File 54558-Review-Webster J.doc
Answering Reviewers 54558-Answering reviewers.pdf
Audio Core Tip 54558-Audio core tip.m4a
Biostatistics Review Certificate 54558-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 54558-Conflict-of-interest statement.pdf
Copyright License Agreement 54558-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54558-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 54558-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 54558-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 54558-Language certificate.pdf
Peer-review Report 54558-Peer-review(s).pdf
Scientific Misconduct Check 54558-Scientific misconduct check.pdf
Scientific Editor Work List 54558-Scientific editor work list.pdf