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Articles Published Processes
5/7/2020 5:03:30 AM | Browse: 790 | Download: 1497
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Received |
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2020-02-11 04:06 |
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Peer-Review Started |
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2020-02-11 04:07 |
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To Make the First Decision |
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Return for Revision |
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2020-02-27 00:38 |
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Revised |
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2020-03-26 11:15 |
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Second Decision |
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2020-04-23 04:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-04-24 01:28 |
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Articles in Press |
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2020-04-24 01:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-29 08:57 |
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Publish the Manuscript Online |
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2020-05-07 05:03 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Assessment of hemostatic profile in patients with mild to advanced liver cirrhosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Elisabeth Hannah Adam, Madara Möhlmann, Eva Herrmann, Sonia Schneider, Kai Zacharowski, Stefan Zeuzem, Christian Friedrich Weber and Nina Weiler |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Elisabeth Hannah Adam, MD, Attending Doctor, Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe-University Frankfurt, Theodor-Stern Kai 7, Frankfurt 60590, Germany. elisabeth.adam@kgu.de |
| Key Words |
Liver cirrhosis; Model for end-stage liver disease; Coagulopathy; Multiple electrode aggregometry; Thrombelastometry; Hemostasis |
| Core Tip |
The results of our study show a moderately decreased platelet aggregation but no substantial impairment of the maximum clot firmness considering thrombelastometric results. Correlation analysis indicated that impedance aggregometric and thrombelastometric results did not correlate with model for end-stage liver disease score. Our data indicate that a potential coagulopathy in advanced liver cirrhosis may not be reflected by thrombelastometry or multiple electrode aggregometry as the underlying mechanisms may be beyond the platelet function of hemostasis. Rather, an individual assessment of a potential coagulopathy in patients with advanced disease is reasonable. |
| Publish Date |
2020-05-07 05:03 |
| Citation |
Adam EH, Möhlmann M, Herrmann E, Schneider S, Zacharowski K, Zeuzem S, Weber CF, Weiler N. Assessment of hemostatic profile in patients with mild to advanced liver cirrhosis. World J Gastroenterol 2020; 26(17): 2097-2110 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i17/2097.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i17.2097 |
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