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Publication Name World Journal of Gastroenterology
Manuscript ID 54634
Country/Territory United Kingdom
2020-02-09 21:27
Peer-Review Started
2020-02-09 21:28
To Make the First Decision
Return for Revision
2020-02-27 00:43
2020-03-25 17:18
Second Decision
2020-04-14 13:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-04-14 23:51
Articles in Press
2020-04-14 23:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-04-29 00:08
Publish the Manuscript Online
2020-05-07 05:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Minireviews
Article Title Radiofrequency combined with immunomodulation for hepatocellular carcinoma: State of the art and innovations
Manuscript Source Unsolicited Manuscript
All Author List Adriano Carneiro da Costa, Mikael Sodergren, Kumar Jayant, Fernando Santa Cruz, Duncan Spalding, Madhava Pai and Nagy Habib
Author(s) ORCID Number
Adriano Carneiro da Costa http://orcid.org/0000-0001-5370-3621
Mikael Sodergren http://orcid.org/0000-0002-7141-3924
Kumar Jayant http://orcid.org/0000-0003-0490-7323
Fernando Santa Cruz http://orcid.org/0000-0002-3178-1036
Duncan Spalding http://orcid.org/0000-0002-6592-9852
Madhava Pai http://orcid.org/0000-0001-9339-7307
Nagy Habib http://orcid.org/0000-0003-4920-4154
Funding Agency and Grant Number
Corresponding author Nagy Habib, FRCS (Gen Surg), Chairman, Professor, Department of Surgery and Cancer, Faculty of Medicine, Hammersmith Hospital, Imperial College London, 1st Floor B Block, Du Cane Road, London W12 0NN, United Kingdom. nagy.habib@imperial.ac.uk
Keywords Hepatocellular carcinoma; Radiofrequency ablation; Immunotherapy; Liver cancer; Combined modality therapy; State-of-the-art review
Core Tip Radiofrequency ablation (RFA) is a well-established surgical approach to treat hepatocellular carcinoma (HCC). However, it has the inconvenience of being related to tumor recurrence. The combination of RFA and immunotherapy has emerged as a promising approach to activate and potentialize local and systemic immune responses. It has potential to reinstate anti-tumor immunity in HCC through increase in antitumor T cell response. The approach seems quite pragmatic in limiting the recurrence and improving survival rates compared to RFA alone for HCC patients. Currently, there are only eight articles in the literature that studied the combination of RFA and immunotherapy.
Publish Date 2020-05-07 05:03
Citation da Costa AC, Sodergren M, Jayant K, Santa Cruz F, Spalding D, Pai M, Habib N. Radiofrequency combined with immunomodulation for hepatocellular carcinoma: State of the art and innovations. World J Gastroenterol 2020; 26(17): 2040-2048
Url https://www.wjgnet.com/1007-9327/full/v26/i17/2040.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i17.2040
Full Article (PDF) WJG-26-2040.pdf
Full Article (Word) WJG-26-2040.docx
Manuscript File 54634-Review.docx
Answering Reviewers 54634-Answering reviewers.pdf
Audio Core Tip 54634-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 54634-Conflict-of-interest statement.pdf
Copyright License Agreement 54634-Copyright license agreement.pdf
Peer-review Report 54634-Peer-review(s).pdf
Scientific Misconduct Check 54634-Scientific misconduct check.pdf
Scientific Editor Work List 54634-Scientific editor work list.pdf