Publication Name	World Journal of Clinical Cases
Manuscript ID	54879
Country	China

Received	2020-02-25 15:13
Peer-Review Started	2020-02-25 15:16
To Make the First Decision
Return for Revision	2020-07-04 01:12
Revised	2020-07-18 16:14
Second Decision	2020-08-13 10:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-08-13 21:18
Articles in Press	2020-08-13 21:18
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-08-25 05:50
Typeset the Manuscript	2020-09-15 17:02
Publish the Manuscript Online	2020-09-22 03:17

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Case Report
Article Title	Gitelman syndrome caused by a rare homozygous mutation in the SLC12A3 gene: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Ri-Zhen Yu and Mao-Sheng Chen
ORCID	Author(s) ORCID Number Ri-Zhen Yu http://orcid.org/0000-0001-5189-3636 Mao-Sheng Chen http://orcid.org/0000-0002-3344-1393
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81700649
Corresponding Author	Mao-Sheng Chen, MD, PhD, Assistant Professor, Doctor, Doctor, Department of Nephrology Division, Zhejiang Provincial People’s Hospital,People’s Hospital of Hangzhou Medical College, No. 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China. maoshengc@126.com
Key Words	Gitelman syndrome; Hypoaclemia; SLC12A3; Homozygous; Rare mutation; Case report
Core Tip	In this manuscript, we reported a case of a patient with severe hypokalemia and diagnosed with Gitelman syndrome by genome sequencing. We found a relatively unusual homozygous mutation in the SLC12A3 gene, which had been rarely reported previously. Besides, this patient had elevated creatinine, different from general Gitelman syndrome, suggesting some factors, including this kind of mutation, might cause renal impairment.
Publish Date	2020-09-22 03:17
Citation	Yu RZ, Chen MS. Gitelman syndrome caused by a rare homozygous mutation in the SLC12A3 gene: A case report. World J Clin Cases 2020; 8(18): 4252-4258
URL	https://www.wjgnet.com/2307-8960/full/v8/i18/4252.htm
DOI	https://dx.doi.org/10.12998/wjcc.v8.i18.4252

Full Article (PDF)	WJCC-8-4252.pdf
Full Article (Word)	WJCC-8-4252.docx
CARE Checklist–2016	54879-CARE-Checklist–2016-revision.pdf
Manuscript File	54879-Review-Webster J.docx
Answering Reviewers	54879-Answering reviewers.pdf
Audio Core Tip	54879-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	54879-Conflict-of-interest statement.pdf
Copyright License Agreement	54879-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	54879-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	54879-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	54879-Language certificate.pdf
Peer-review Report	54879-Peer-review(s).pdf
Scientific Misconduct Check	54879-Bing-Wang JL-1.jpg
Scientific Misconduct Check	54879-Scientific misconduct check.pdf
Scientific Editor Work List	54879-Scientific editor work list.pdf
CrossCheck Report	54879-CrossCheck report.pdf