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Articles Published Processes
6/28/2020 10:42:01 AM | Browse: 684 | Download: 1327
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Received |
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2020-02-26 15:14 |
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Peer-Review Started |
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2020-02-26 15:15 |
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To Make the First Decision |
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Return for Revision |
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2020-05-01 02:54 |
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Revised |
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2020-05-11 22:42 |
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Second Decision |
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2020-06-09 09:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-06-10 17:45 |
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Articles in Press |
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2020-06-10 17:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-06-27 08:31 |
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Publish the Manuscript Online |
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2020-06-28 10:42 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Review |
Article Title |
Intestinal Ca2+ absorption revisited: A molecular and clinical approach
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Manuscript Source |
Invited Manuscript |
All Author List |
Vanessa A Areco, Romina Kohan, Germán Talamoni, Nori G Tolosa de Talamoni and María E Peralta López |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Consejo Nacional de Investigaciones Científicas y Tecnológicas, Argentina PIP 2017-2019 |
11220170100012CO |
Secretaría de Ciencia y Técnica de la Universidad Nacional de Córdoba, Argentina (Programa 2018-2019) |
30920180100056CB |
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Corresponding Author |
Nori G Tolosa de Talamoni, PhD, Professor, Laboratorio “Dr. Fernando Cañas”, Cátedra de Bioquímica y Biología Molecular, Facultad de Ciencias Médicas, INICSA (CONICET-Universidad Nacional de Córdoba), Pabellón Argentina, 2do. Piso, Ciudad Universitaria, Córdoba 5000, Argentina. ntolosa@biomed.fcm.unc.edu.ar |
Key Words |
Ca2+ absorption; Transcellular pathway; Paracellular pathway; Hormones; Dietary calcium; Physiological conditions |
Core Tip |
The intestinal Ca2+ absorption occurs mainly via the paracellular and the transcellular pathways. Both ways are regulated by calcitriol and other hormones as well as dietary factors. Fibroblast growth factor is a strong antagonist of vitamin D action. Part of the intestinal Ca2+ movement seems to be vitamin D independent. Intestinal Ca2+ absorption changes according to different physiological conditions. Oxidative stress inhibits the intestinal Ca2+ absorption whereas the antioxidants counteract the prooxidant effects. Most diseases that occur with altered intestinal Ca2+ absorption is related to changes in the vitamin D endocrine system. Further research could clarify many unknown points in this subject. |
Publish Date |
2020-06-28 10:42 |
Citation |
Areco VA, Kohan R, Talamoni G, Tolosa de Talamoni NG, Peralta López ME. Intestinal Ca2+ absorption revisited: A molecular and clinical approach. World J Gastroenterol 2020; 26(24): 3344-3364 |
URL |
https://www.wjgnet.com/1007-9327/full/v26/i24/3344.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v26.i24.3344 |
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