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Articles Published Processes
5/26/2020 2:31:16 PM | Browse: 889 | Download: 1612
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Received |
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2020-02-27 17:23 |
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Peer-Review Started |
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2020-02-27 17:23 |
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To Make the First Decision |
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Return for Revision |
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2020-04-07 23:24 |
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Revised |
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2020-04-19 15:20 |
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Second Decision |
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2020-04-29 12:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-05 15:13 |
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Articles in Press |
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2020-05-05 15:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-05-14 03:51 |
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Publish the Manuscript Online |
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2020-05-26 14:31 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Molecular modulation of autophagy: New venture to target resistant cancer stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Harpreet K Mandhair, Miroslav Arambasic, Urban Novak and Ramin Radpour |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ramin Radpour, MSc, PhD, Lecturer, Senior Researcher, Tumor Immunology, Department for BioMedical Research (DBMR), University of Bern, Murtenstrasse 35, Bern 3008, Switzerland. ramin.radpour@dbmr.unibe.ch |
| Key Words |
Autophagy; Cancer stem cells; Cancer cells; Cancer therapy; Therapeutic resistance; Cancer metastasis |
| Core Tip |
Cancer stem cells (CSCs) are a distinct subpopulation in the tumor bulk that are highly plastic, and autophagy has been suggested to modulate their stemness and development during cancer progression. Autophagy is a pro-survival mechanism used by cancer cells to provide bioenergetic substrates. Therefore, dissecting the role of autophagy in cancer propagation can theoretically lead to a more efficient cancer treatment via the modulation of autophagy, in combination with chemotherapeutics to sensitize and target CSCs. This review summarizes the divergent role of autophagy in CSCs and cancer cells and attempts to elucidate the molecular mechanisms involved. |
| Publish Date |
2020-05-26 14:31 |
| Citation |
Mandhair HK, Arambasic M, Novak U, Radpour R. Molecular modulation of autophagy: New venture to target resistant cancer stem cells. World J Stem Cells 2020; 12(5): 303-322 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i5/303.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i5.303 |
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