Publication Name	World Journal of Gastroenterology
Manuscript ID	5528
Country	Taiwan

Received	2013-09-13 08:48
Peer-Review Started	2013-09-13 12:20
To Make the First Decision	2013-10-22 16:09
Return for Revision	2013-10-15 19:57
Revised	2013-10-16 13:53
Second Decision	2014-01-02 11:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-01-02 12:13
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-01-09 07:56
Typeset the Manuscript	2014-01-16 11:25
Publish the Manuscript Online	2014-03-12 14:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Irritable bowel syndrome: The evolution of multi-dimensional looking and multidisciplinary treatments
Manuscript Source	Invited Manuscript
All Author List	Full-Young Chang
Funding Agency and Grant Number
Corresponding Author	Full-Young Chang, MD, Professor, Environmental Health and Safety Office and Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine, 201 Shih-Pai Road, Section 2, Taipei 11217, Taiwan. changfy@vghtpe.gov.tw
Key Words	Antispasmodics; Biopsychosocial dysfunction; Comorbidity; Genetics; Irritable bowel syndrome; Microbiota; Probiotics; Visceral hyperalgesia
Core Tip	Irritable bowel syndrome (IBS) is common in the society. Patients with this disorder have a poor quality of life with severe impact on their social and economic burdens. Its pathogenesis remains evolutional, involving biological, psychiatric and social factors. Therefore, the biopsychosocial dysfunctional model has attempted to integrate all the above mentioned mechanisms in order to understand how IBS can develop under such complex interaction. Since the etiology of IBS is heterogeneous, the currently recommended treatments are multidisciplinary and also individualized, e.g., using different classes of drugs, psychiatric measures, probiotics and antibiotics, dietary therapy, and finally complementary and alternative medicines.
Publish Date	2014-03-12 14:46
Citation	Chang FY. Irritable bowel syndrome: The evolution of multi-dimensional looking and multidisciplinary treatments. World J Gastroenterol 2014; 20(10): 2499-2514
URL	http://www.wjgnet.com/1007-9327/full/v20/i10/2499.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i10.2499

Full Article (PDF)	WJG-20-2499.pdf
Full Article (Word)	WJG-20-2499.doc
Manuscript File	5528-Review.docx
Answering Reviewers	5528-Answering Reviewers.pdf
Copyright License Agreement	5528-Copyright assignment.pdf
Peer-review Report	5528-Peer review(s).pdf
Scientific Editor Work List	5528-Scientific editor work list.doc