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12/19/2020 11:55:31 AM | Browse: 570 | Download: 1070
Publication Name World Journal of Gastroenterology
Manuscript ID 55373
Country/Territory China
Received
2020-08-21 10:21
Peer-Review Started
2020-08-21 10:21
To Make the First Decision
Return for Revision
2020-10-18 00:21
Revised
2020-10-31 08:48
Second Decision
2020-11-12 09:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-11-12 20:13
Articles in Press
2020-11-12 20:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-11-22 00:41
Typeset the Manuscript
2020-12-17 03:11
Publish the Manuscript Online
2020-12-19 11:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Therapeutic efficiency of bone marrow-derived mesenchymal stem cells for liver fibrosis: A systematic review of in vivo studies
Manuscript Source Unsolicited Manuscript
All Author List Zaid Al-Dhamin, Ling-Di Liu, Dong-Dong Li, Si-Yu Zhang, Shi-Ming Dong and Yue-Min Nan
ORCID
Author(s) ORCID Number
Zaid Al-Dhamin http://orcid.org/0000-0002-0503-2592
Ling-Di Liu http://orcid.org/0000-0003-4286-5603
Dong-Dong Li http://orcid.org/0000-0002-4210-5551
Si-Yu Zhang http://orcid.org/0000-0002-7979-4610
Shi-Ming Dong http://orcid.org/0000-0003-33621-1443
Yue-Min Nan http://orcid.org/0000-0003-4192-099X
Funding Agency and Grant Number
Funding Agency Grant Number
Key Research and Development Program of Hebei Province 19277779D
The Program of Introduce International Intelligence of Hebei Province
Corresponding Author Yue-Min Nan, MD, PhD, Director, Doctor, Professor, Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University & Hebei Key Laboratory of Mechanism of Liver Fibrosis in Chronic Liver Disease, No. 139 Ziqiang Road, Shijiazhuang 050051, Hebei Province, China. nanyuemin@163.com
Key Words Bone marrow; Mesenchymal stem cells; Liver fibrosis; In vivo; Efficiency;
Core Tip Bone marrow (BM)-derived mesenchymal stem cells (MSCs) are a promising therapy for liver fibrosis. However, several aspects of this treatment are vague, such as efficiency. This review summarizes the recent advances and studies the effectiveness of BM-MSC therapy, its mechanisms and related factors, focusing on the preclinical in vivo experiments. While BM-MSCs appear to be effective in some cases, in others, the cotreatment appears to be the better option. Studies on strategies, implementation routes, and cotreatments are helping to strengthen the therapy's efficiency. While the potential of this therapy continues to advance, research is still needed to achieve full potential.
Publish Date 2020-12-19 11:55
Citation Al-Dhamin Z, Liu LD, Li DD, Zhang SY, Dong SM, Nan YM. Therapeutic efficiency of bone marrow-derived mesenchymal stem cells for liver fibrosis: A systematic review of in vivo studies. World J Gastroenterol 2020; 26(47): 7444-7469
URL https://www.wjgnet.com/1007-9327/full/v26/i47/7444.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i47.7444
Full Article (PDF) WJG-26-7444.pdf
Full Article (Word) WJG-26-7444.docx
Manuscript File 55373-Review-Filipodia.docx
Answering Reviewers 55373-Answering reviewers.pdf
Audio Core Tip 55373-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 55373-Conflict-of-interest statement.pdf
Copyright License Agreement 55373-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55373-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 55373-Language certificate.pdf
Peer-review Report 55373-Peer-review(s).pdf
Scientific Misconduct Check 55373-Bing-Yan JP-1.png
Scientific Misconduct Check 55373-Scientific misconduct check.pdf
Scientific Editor Work List 55373-Scientific editor work list.pdf