7/21/2020 1:23:48 PM | Browse: 825 | Download: 1844
| Publication Name | World Journal of Gastroenterology |
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| Manuscript ID | 55430 |
| Country | China |
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| ISSN | 1007-9327 (print) and 2219-2840 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright | © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Gastroenterology & Hepatology | ||||||||||||||||||
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| Manuscript Type | Retrospective Study | ||||||||||||||||||
| Article Title | Serum ceruloplasmin can predict liver fibrosis in hepatitis B virus-infected patients | ||||||||||||||||||
| Manuscript Source | Unsolicited Manuscript | ||||||||||||||||||
| All Author List | Na-Ling Kang, Jie-Min Zhang, Meng-Xin Lin, Xu-Dong Chen, Zu-Xiong Huang, Yue-Yong Zhu, Yu-Rui Liu and Da-Wu Zeng | ||||||||||||||||||
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| Corresponding Author | Da-Wu Zeng, MD, PhD, Associate Chief Physician, Doctor, Doctor, Liver Center, The First Affiliated Hospital, Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. zengdw1980@fjmu.edu.cn | ||||||||||||||||||
| Key Words | Ceruloplasmin; Liver fibrosis; Chronic hepatitis B infection; Serum alanine aminotransferase; Noninvasive model; Receiver-operating characteristic | ||||||||||||||||||
| Core Tip | Chronic hepatitis B virus (HBV)-infected individuals with persistently normal serum alanine aminotransferase levels (PNALT) may develop severe liver fibrosis, which requires antiviral therapy. Following up on our previous findings, this multicenter, cross-sectional study showed that ceruloplasmin (CP) has an inverse correlation with liver fibrosis and is a promising predictive marker for liver fibrosis among HBV-infected individuals with PNALT. We developed a noninvasive model using CP, platelet, and HBsAg levels to identify the various stages of fibrosis among HBV-infected individuals with PNALT. Our model could reduce the need for liver biopsy before antiviral treatment. | ||||||||||||||||||
| Publish Date | 2020-07-21 13:23 | ||||||||||||||||||
| Citation | Kang NL, Zhang JM, Lin MX, Chen XD, Huang ZX, Zhu YY, Liu YR, Zeng DW. Serum ceruloplasmin can predict liver fibrosis in hepatitis B virus-infected patients. World J Gastroenterol 2020; 26(27): 3952-3962 | ||||||||||||||||||
| URL | https://www.wjgnet.com/1007-9327/full/v26/i27/3952.htm | ||||||||||||||||||
| DOI | https://dx.doi.org/10.3748/wjg.v26.i27.3952 |
| Full Article (PDF) | WJG-26-3952.pdf |
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| Full Article (Word) | WJG-26-3952.docx |
| Manuscript File | 55430-Review_WangTQ.docx |
| Answering Reviewers | 55430-Answering reviewers.pdf |
| Audio Core Tip | 55430-Audio core tip.m4a |
| Biostatistics Review Certificate | 55430-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | 55430-Conflict-of-interest statement.pdf |
| Copyright License Agreement | 55430-Copyright license agreement.pdf |
| Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) | 55430-Grant application form(s).pdf |
| Signed Informed Consent Form(s) or Document(s) | 55430-Informed consent statement.pdf |
| Institutional Review Board Approval Form or Document | 55430-Institutional review board statement.pdf |
| Non-Native Speakers of English Editing Certificate | 55430-Language certificate.pdf |
| Supplementary Material | 55430-Supplementary material.pdf |
| Peer-review Report | 55430-Peer-review(s).pdf |
| Scientific Misconduct Check | 55430-Bing-Dou Y-2.png |
| Scientific Misconduct Check | 55430-Scientific misconduct check.pdf |
| Scientific Editor Work List | 55430-Scientific editor work list.pdf |
| CrossCheck Report | 55430-CrossCheck report.pdf |