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7/21/2020 1:23:48 PM | Browse: 685 | Download: 1186
Publication Name World Journal of Gastroenterology
Manuscript ID 55430
Country/Territory China
Received
2020-03-17 12:07
Peer-Review Started
2020-03-17 12:07
To Make the First Decision
Return for Revision
2020-04-25 05:41
Revised
2020-05-06 14:30
Second Decision
2020-06-29 10:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-06-29 22:31
Articles in Press
2020-06-29 22:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-07-03 02:21
Typeset the Manuscript
2020-07-20 06:59
Publish the Manuscript Online
2020-07-21 13:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Serum ceruloplasmin can predict liver fibrosis in hepatitis B virus-infected patients
Manuscript Source Unsolicited Manuscript
All Author List Na-Ling Kang, Jie-Min Zhang, Meng-Xin Lin, Xu-Dong Chen, Zu-Xiong Huang, Yue-Yong Zhu, Yu-Rui Liu and Da-Wu Zeng
ORCID
Author(s) ORCID Number
Na-Ling Kang http://orcid.org/0000-0001-6923-5754
Jie-Min Zhang http://orcid.org/0000-0003-2190-3412
Meng-Xin Lin http://orcid.org/0000-0003-1621-4524
Xu-Dong Chen http://orcid.org/0000-0003-2531-8122
Zu-Xiong Huang http://orcid.org/0000-0003-0994-0384
Yue-Yong Zhu http://orcid.org/0000-0002-0746-4911
Yu-Rui Liu http://orcid.org/0000-0003-0553-846X
Da-Wu Zeng http://orcid.org/0000-0003-3818-0062
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Department of Fujian Province 2018J01164
Quanzhou Science and Technology Bureau Planning Project 2019N019S
Corresponding Author Da-Wu Zeng, MD, PhD, Associate Chief Physician, Doctor, Liver Center, The First Affiliated Hospital, Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. zengdw1980@fjmu.edu.cn
Key Words Ceruloplasmin; Liver fibrosis; Chronic hepatitis B infection; Serum alanine aminotransferase; Noninvasive model; Receiver-operating characteristic
Core Tip Chronic hepatitis B virus (HBV)-infected individuals with persistently normal serum alanine aminotransferase levels (PNALT) may develop severe liver fibrosis, which requires antiviral therapy. Following up on our previous findings, this multicenter, cross-sectional study showed that ceruloplasmin (CP) has an inverse correlation with liver fibrosis and is a promising predictive marker for liver fibrosis among HBV-infected individuals with PNALT. We developed a noninvasive model using CP, platelet, and HBsAg levels to identify the various stages of fibrosis among HBV-infected individuals with PNALT. Our model could reduce the need for liver biopsy before antiviral treatment.
Publish Date 2020-07-21 13:23
Citation Kang NL, Zhang JM, Lin MX, Chen XD, Huang ZX, Zhu YY, Liu YR, Zeng DW. Serum ceruloplasmin can predict liver fibrosis in hepatitis B virus-infected patients. World J Gastroenterol 2020; 26(27): 3952-3962
URL https://www.wjgnet.com/1007-9327/full/v26/i27/3952.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i27.3952
Full Article (PDF) WJG-26-3952.pdf
Full Article (Word) WJG-26-3952.docx
Manuscript File 55430-Review_WangTQ.docx
Answering Reviewers 55430-Answering reviewers.pdf
Audio Core Tip 55430-Audio core tip.m4a
Biostatistics Review Certificate 55430-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 55430-Conflict-of-interest statement.pdf
Copyright License Agreement 55430-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55430-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 55430-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 55430-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 55430-Language certificate.pdf
Supplementary Material 55430-Supplementary material.pdf
Peer-review Report 55430-Peer-review(s).pdf
Scientific Misconduct Check 55430-Bing-Dou Y-2.png
Scientific Misconduct Check 55430-Scientific misconduct check.pdf
Scientific Editor Work List 55430-Scientific editor work list.pdf