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Articles Published Processes
11/25/2020 2:44:03 PM | Browse: 406 | Download: 862
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Received |
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2020-04-05 16:12 |
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Peer-Review Started |
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2020-04-05 16:12 |
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To Make the First Decision |
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Return for Revision |
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2020-09-24 22:24 |
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Revised |
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2020-10-06 17:12 |
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Second Decision |
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2020-10-13 12:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-10-20 04:03 |
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Articles in Press |
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2020-10-20 04:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-26 03:13 |
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Typeset the Manuscript |
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2020-11-18 09:30 |
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Publish the Manuscript Online |
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2020-11-25 14:44 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Primary myelofibrosis with concurrent CALR and MPL mutations: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Feng-Ping Zhou, Cheng-Cheng Wang, Hua-Ping Du, Shan-Bo Cao and Jin Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jin Zhang, MD, Attending Doctor, Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. zfpingzd@zju.edu.cn |
| Key Words |
Primary myelofibrosis; CALR; MPL; Co-mutation; Next-generation sequencing; Case report |
| Core Tip |
We report a rare case of primary myelofibrosis in which a CALR and MPL co-mutation was detected with next-generation sequencing technology. It demonstrates that CALR and MPL mutations can be concurrent in myeloproliferative neoplasm. We review the literature, analyze previous reports of the mutation sites in our patient and differences between our patient and other reported cases of co-mutated CALR and MPL genes, discuss the reason why the CALR and MPL co-mutations are rare and possible mechanisms and their impact on the prognosis of patients. |
| Publish Date |
2020-11-25 14:44 |
| Citation |
Zhou FP, Wang CC, Du HP, Cao SB, Zhang J. Primary myelofibrosis with concurrent CALR and MPL mutations: A case report. World J Clin Cases 2020; 8(22): 5618-5624 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i22/5618.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i22.5618 |
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