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Articles Published Processes
8/24/2020 10:40:39 AM | Browse: 967 | Download: 1896
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Received |
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2020-04-07 17:21 |
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Peer-Review Started |
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2020-04-07 17:22 |
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First Decision by Editorial Office Director |
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2020-06-20 21:55 |
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Return for Revision |
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2020-06-20 21:55 |
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Revised |
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2020-07-02 14:27 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2020-07-17 10:09 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-07-19 20:54 |
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Articles in Press |
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2020-07-19 20:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-08-24 05:45 |
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Publish the Manuscript Online |
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2020-08-24 10:40 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Minireviews |
| Article Title |
Geometric architecture of viruses
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mohammad Khalid Parvez |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammad Khalid Parvez, PhD, Associate Professor, Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 22451, Saudi Arabia. khalid_parvez@yahoo.com |
| Key Words |
Virus; Virion; Capsid structure; Icosahedron; Triangulation number; |
| Core Tip |
A detailed structural knowledge of a pathogenic virus is essential for understanding the mechanisms of capsid assembly, antigenicity, cell receptor interaction, and designing therapeutic strategies. X-ray crystallography, cryo-electron microscopy and molecular simulations have elucidated atomic-level structures of several viruses. Notably, a recently determined crystal structure of SARS-CoV-2 capsid has revealed its close similarity to that of SARS-CoV-1 and MERS-CoV. Capsid symmetry greatly contributes to virion stability and balance between genome. Enveloped icosahedral viruses are very common in animals, and rare in plants. Several of self-assembled, stable and non-infectious virus-like particles have been widely exploited as vaccine candidates and therapeutic molecules delivery vehicles. |
| Publish Date |
2020-08-24 10:40 |
| Citation |
Parvez MK. Geometric architecture of viruses. World J Virol 2020; 9(2): 5-18
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| URL |
https://www.wjgnet.com/2220-3249/full/v9/i2/5.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v9.i2.5 |
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