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Articles Published Processes
8/20/2014 6:38:00 PM | Browse: 1050 | Download: 1010
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Received |
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2013-09-17 12:22 |
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Peer-Review Started |
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2013-09-17 16:41 |
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To Make the First Decision |
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2013-12-26 11:34 |
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Return for Revision |
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2014-05-23 15:10 |
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Revised |
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2014-06-03 11:03 |
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Second Decision |
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2014-06-26 16:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-06-26 17:29 |
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Articles in Press |
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2014-06-26 17:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-07-11 21:45 |
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Typeset the Manuscript |
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2014-08-07 18:32 |
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Publish the Manuscript Online |
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2014-08-20 18:38 |
Category |
Transplantation |
Manuscript Type |
Topic Highlights |
Article Title |
Clinical mycophenolic acid monitoring in liver transplant recipients
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Manuscript Source |
Invited Manuscript |
All Author List |
Hao Chen and Bing Chen |
Funding Agency and Grant Number |
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Corresponding Author |
Hao Chen, PhD, Center of Organ Transplantation and Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Erlu, Shanghai 200240, China. haochendr@126.com |
Key Words |
Mycophenolate mofetil; Mycophenolic acid; Pharmacokinetics; Therapeutic drug monitoring; Liver transplantation |
Core Tip |
We discussed the methods of mycophenolic acid (MPA) monitoring, pharmacokinetic characteristics, clinical exposure related to acute rejection and mycophenolate mofetil (MMF) associated side effects in liver transplant recipients. We also introduced the methods of limited sampling strategies to predict the MPA area under the concentration-time curve. It demonstrated that a fixed-dosage MMF regimen might not be suitable. In clinical settings, monitoring of MPA exposure seems reasonable and necessary. |
Publish Date |
2014-08-20 18:38 |
Citation |
Chen H, Chen B. Clinical mycophenolic acid monitoring in liver transplant recipients. World J Gastroenterol 2014; 20(31): 10715-10728 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i31/10715.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i31.10715 |
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