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Articles Published Processes
10/16/2020 9:14:42 AM | Browse: 939 | Download: 1917
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Received |
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2020-06-16 00:10 |
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Peer-Review Started |
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2020-06-16 00:11 |
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To Make the First Decision |
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Return for Revision |
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2020-07-21 16:20 |
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Revised |
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2020-07-31 00:51 |
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Second Decision |
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2020-08-24 12:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-08-25 05:22 |
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Articles in Press |
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2020-08-25 05:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-09-03 01:56 |
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Publish the Manuscript Online |
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2020-10-16 09:14 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Case Control Study |
| Article Title |
Association between thrombomodulin and high mobility group box 1 in sepsis patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Adriana Teixeira Rodrigues, Julia Teixeira Rodrigues, Carolina Teixeira Rodrigues, Caroline Maria de Oliveira Volpe, Fabiana Rocha-Silva, Jose Augusto Nogueira-Machado and Luiz Ronaldo Alberti |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Adriana Teixeira Rodrigues, MD, MSc, Assistant Professor, Attending Doctor, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais, 190, Alfredo Balena Avenue, Belo Horizonte 30130-100, Minas Gerais, Brazil. adrianatr92@gmail.com |
| Key Words |
High mobility group box 1; Sepsis; Thrombomodulin; Renal replacement therapy; Mechanical ventilation; Septic shock |
| Core Tip |
The knowledge of physiological mechanisms that lead an organism to respond to an infectious agent with such intensity is of great importance. It has been described that during sepsis, an organism produces intense inflammatory activity, caused by the action of several inflammatory mediators. High mobility group box 1 (HMGB1) has been the target of recent studies for its proinflammatory actions as well as for the possibility of having its action reduced by thrombomodulin. For this reason, this study proposed to evaluate the relationship between thrombomodulin and HMGB1 in the initial phase of sepsis and its association with clinical outcomes in sepsis patients. |
| Publish Date |
2020-10-16 09:14 |
| Citation |
Rodrigues AT, Rodrigues JT, Rodrigues CT, Volpe CMO, Rocha-Silva F, Nogueira-Machado JA, Alberti LR. Association between thrombomodulin and high mobility group box 1 in sepsis patients. World J Crit Care Med 2020; 9(4): 63-73 |
| URL |
https://www.wjgnet.com/2220-3141/full/v9/i4/63.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v9.i4.63 |
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