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Articles Published Processes
10/24/2020 2:27:21 AM | Browse: 847 | Download: 1155
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Received |
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2020-05-21 19:42 |
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Peer-Review Started |
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2020-05-20 18:26 |
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To Make the First Decision |
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Return for Revision |
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2020-07-31 02:56 |
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Revised |
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2020-08-02 20:11 |
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Second Decision |
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2020-08-24 12:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-08-25 23:47 |
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Articles in Press |
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2020-08-25 23:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-09-11 03:18 |
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Publish the Manuscript Online |
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2020-10-24 02:27 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Toxicology |
| Manuscript Type |
Case Report |
| Article Title |
Kratom induced severe cholestatic liver injury histologically mimicking primary biliary cholangitis: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Darshan Gandhi, Kriti Ahuja, Alexis Quade, Kenneth P. Batts and Love Patel |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Darshan Gandhi, MD, Academic Fellow, Doctor, Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N St. Clair St, Suite 800, Chicago, IL 60611, United States. darshangandhi7@gmail.com |
| Key Words |
Case report; Kratom; Cholestasis; Liver injury; Mitragyna speciosa; Cholangitis |
| Core Tip |
Kratom induced liver injury is an important differential diagnosis for physicians to consider in any patient presenting with acute liver injury. As observed in our patient, this manifestation of kratom consumption may occur even at low doses. Further, this case report demonstrates that a thorough history is essential for an accurate and timely diagnosis. Patients may consider dietary and herb supplements to be natural and risk-free products, not realizing the potential for harm. In addition to asking their patients about consumption of any supplements, it is imperative that physicians update themselves so as to be able to discuss the benefits and risks, and counsel their patients effectively. Identifying use of supplements helps in early diagnosis and treatment, while also preventing future harm. From the pathology perspective, biliary changes associated with Kratom injury can mimic PBC. |
| Publish Date |
2020-10-24 02:27 |
| Citation |
Gandhi D, Ahuja K, Quade A, Batts KP, Patel L. Kratom induced severe cholestatic liver injury histologically mimicking Primary Biliary Cholangitis: A case report. World J Hepatol 2020; 12(10): 863-869 |
| URL |
https://www.wjgnet.com/1948-5182/full/v12/i10/863.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v12.i10.863 |
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