| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Yoshiki Sakaguchi, Yousuke Nakai, Hidenobu Watanabe, Hidekazu Suzuki, Chizu Tanikawa, Koichi Matsuda and Kazuhiko Koike |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Education, Culture, Sports, Science and Technology of Japan |
25134707 |
| Ministry of Education, Culture, Sports, Science and Technology of Japan |
16H01566 |
| Ministry of Education, Culture, Sports, Science and Technology of Japan |
15K14377 |
| funding from the Tailor-Made Medical Treatment with the BBJ Project from Japan Agency for Medical Research and Development, AMED (from April 2015) |
|
| the Ministry of Education, Culture, Sports, Science, and Technology of Japan (from April 2003 to March 2015) |
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| Corresponding Author |
Osamu Toyoshima, MD, Doctor, Department of Gastroenterology, Toyoshima Endoscopy Clinic, 6-17-5 Seijo, Setagaya-ku, Tokyo 157-0066, Japan. t@ichou.com |
| Key Words |
Kyoto classification; Helicobacter pylori; Neutrophil activity; Updated Sydney System; Gastritis; Gastric cancer |
| Core Tip |
We investigated the association between endoscopy-based Kyoto classification of gastritis and pathologically topographic distribution of neutrophil activity which related to gastric cancer risk. Kyoto classification score is consisted of atrophy, intestinal metaplasia, enlarged folds, nodularity, and diffuse redness. The subjects were divided into four categories, inactive stomach, antrum-predominant gastritis, pangastritis, and corpus-predominant gastritis, based on distribution of neutrophil activity. Kyoto scores were higher in the order of inactive stomach, antrum-predominant gastritis, pangastritis, and corpus-predominant gastritis. On multivariate analysis, Kyoto score was independently associated with topographic distribution of neutrophil activity. In conclusion, Kyoto classification score was associated with gastric cancer risk. |
| Publish Date |
2020-09-09 11:11 |
| Citation |
Toyoshima O, Nishizawa T, Yoshida S, Sakaguchi Y, Nakai Y, Watanabe H, Suzuki H, Tanikawa C, Matsuda K, Koike K. Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity. World J Gastroenterol 2020; 26(34): 5146-5155 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i34/5146.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i34.5146 |
