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10/14/2020 11:33:23 AM | Browse: 669 | Download: 1260
Publication Name World Journal of Gastroenterology
Manuscript ID 57071
Country China
Received
2020-05-26 13:12
Peer-Review Started
2020-05-26 13:13
To Make the First Decision
Return for Revision
2020-07-29 04:05
Revised
2020-08-08 18:13
Second Decision
2020-08-25 02:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-25 22:05
Articles in Press
2020-08-25 22:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-09-09 03:28
Typeset the Manuscript
2020-10-08 02:19
Publish the Manuscript Online
2020-10-14 11:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Acetyl-11-keto-β-boswellic acid inhibits proliferation and induces apoptosis of gastric cancer cells through the phosphatase and tensin homolog /Akt/ cyclooxygenase-2 signaling pathway
Manuscript Source Invited Manuscript
All Author List Meng-Xue Sun, Xiao-Pu He, Pei-Yun Huang, Qi Qi, Wei-Hao Sun, Gao-Shuang Liu and Jie Hua
ORCID
Author(s) ORCID Number
Meng-Xue Sun http://orcid.org/0000-0002-2984-1087
Xiao-Pu He http://orcid.org/0000-0002-9915-5584
Pei-Yun Huang http://orcid.org/0000-0003-1070-0724
Qi Qi http://orcid.org/0000-0001-9333-6299
Wei-Hao Sun http://orcid.org/0000-0002-3507-3889
Gao-Shuang Liu http://orcid.org/0000-0001-8450-7308
Jie Hua http://orcid.org/0000-0003-1243-0596
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Jiangsu BK20171508, DA17
Corresponding Author Jie Hua, Assistant Statistician, Doctor, Department of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road , Nanjing 210000, Jiangsu Province, China. huajie@njmu.edu.cn
Key Words Acetyl-11-keto-β-boswellic acid; Gastric cancer; Cell proliferation; Apoptosis; Cyclooxygenase-2; Tumor xenograft
Core Tip Cyclooxygenase-2 is involved in the carcinogenesis and development of gastric cancer, and is closely related to its prognosis. Acetyl-11-keto-β-boswellic acid is a promising drug for gastric cancer therapy. It inhibits proliferation and induces apoptosis of gastric cancer cells, possibly mediated by down-regulation of cyclooxygenase-2 expression through the phosphatase and tensin homolog /Akt signaling pathway.
Publish Date 2020-10-14 11:33
Citation Sun MX, He XP, Huang PY, Qi Q, Sun WH, Liu GS, Hua J. Acetyl-11-keto-β-boswellic acid inhibits proliferation and induces apoptosis of gastric cancer cells through the phosphatase and tensin homolog /Akt/ cyclooxygenase-2 signaling pathway. World J Gastroenterol 2020; 26(38): 5822-5835
URL https://www.wjgnet.com/1007-9327/full/v26/i38/5822.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i38.5822
Full Article (PDF) WJG-26-5822.pdf
Full Article (Word) WJG-26-5822.docx
Manuscript File 57071-Review_WangTQ.docx
Answering Reviewers 57071-Answering reviewers.pdf
Audio Core Tip 57071-Audio core tip.mp3
Biostatistics Review Certificate 57071-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57071-Conflict-of-interest statementn.pdf
Copyright License Agreement 57071-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57071-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 57071-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 57071-Language certificate.pdf
Peer-review Report 57071-Peer-review(s).pdf
Scientific Misconduct Check 57071-Scientific misconduct check.pdf
Scientific Editor Work List 57071-Scientific editor work list.pdf