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Articles Published Processes
8/28/2020 3:06:40 PM | Browse: 835 | Download: 2053
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Received |
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2020-05-30 22:13 |
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Peer-Review Started |
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2020-05-30 22:14 |
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To Make the First Decision |
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Return for Revision |
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2020-06-12 17:59 |
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Revised |
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2020-07-30 21:48 |
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Second Decision |
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2020-08-14 09:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-08-14 16:50 |
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Articles in Press |
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2020-08-14 16:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-08-28 03:13 |
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Publish the Manuscript Online |
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2020-08-28 15:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Inactive matrix Gla protein is elevated in patients with inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Darko Brnic, Dinko Martinovic, Piero Marin Zivkovic, Daria Tokic, Marino Vilovic, Doris Rusic, Ivana Tadin Hadjina, Christian Libers, Sandro Glumac, Daniela Supe-Domic, Ante Tonkic and Josko Bozic |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Josko Bozic, MD, PhD, Associate Professor, Department of Pathophysiology, University of Split School of Medicine, Soltanska 2, Split 21000, Croatia. josko.bozic@mefst.hr |
| Key Words |
Matrix Gla protein; Inflammatory bowel disease; Fecal calprotectin; Ulcerative colitis; Crohn's disease; |
| Core Tip |
Matrix Gla protein is well-established as a protector against vascular calcification. Recent studies pointed to a possible link between Matrix gla protein and inflammatory bowel disease. Our study found significantly higher inactive plasma Matrix Gla protein (MGP) levels in patients with inflammatory bowel disease (IBD) compared to the healthy controls and there were no differences between patients with ulcerative colitis and Crohn’s disease. Furthermore, there was a significant positive correlation between inactive plasma MGP levels with both fecal calprotectin and high sensitivity C-reactive protein levels. These results imply that MGP is somehow involved in complex IBD pathophysiology. |
| Publish Date |
2020-08-28 15:06 |
| Citation |
Brnic D, Martinovic D, Zivkovic PM, Tokic D, Vilovic M, Rusic D, Tadin Hadjina I, Libers C, Glumac S, Supe-Domic D, Tonkic A, Bozic J. Inactive matrix Gla protein is elevated in patients with inflammatory bowel disease. World J Gastroenterol 2020; 26(32): 4866-4877 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i32/4866.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i32.4866 |
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