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Articles Published Processes
9/28/2020 1:45:47 AM | Browse: 977 | Download: 2352
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Received |
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2020-06-04 01:49 |
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Peer-Review Started |
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2020-06-04 01:50 |
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First Decision by Editorial Office Director |
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2020-07-25 04:11 |
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Return for Revision |
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2020-07-25 04:11 |
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Revised |
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2020-07-30 09:42 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2020-08-28 12:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-08-29 02:00 |
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Articles in Press |
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2020-08-29 02:00 |
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Edit the Manuscript by Language Editor |
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2020-09-02 00:50 |
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Typeset the Manuscript |
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2020-09-24 09:51 |
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Publish the Manuscript Online |
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2020-09-28 01:45 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Public, Environmental & Occupational Health |
| Manuscript Type |
Case Control Study |
| Article Title |
Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mian Wang, Shu-Juan Ma, Xin-Yin Wu, Xian Zhang, Julius Abesig, Zheng-Hui Xiao, Xin Huang, Hai-Peng Yan, Jing Wang, Meng-Shi Chen and Hong-Zhuan Tan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
81803298 |
| Hunan Provincial Natural Science Foundation of China |
2020JJ4762 |
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| Corresponding Author |
Meng-Shi Chen, PhD, Lecturer, Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, No. 110 Xiangya Road, Changsha 410078, Hunan Province, China. 121444639@qq.com |
| Key Words |
Tuberculosis; mTOR; Tea drinking; Gene-environment interaction; The relative excess risk of interaction; Single nucleotide polymorphism |
| Core Tip |
Our data demonstrated that genotypes GT, GG, and GT + GG at rs2295080; genotypes CT and CT + TT at rs2024627; genotypes CT, CC and CT + CC at rs1057079; and genotypes CT and CT + CC at rs7525957 of mTOR gene are associated with statistically increased risk of tuberculosis in a Chinese population. In addition, there was a negative interaction between each of the four single nucleotide polymorphism (SNPs) and tea drinking. These findings may be helpful for identifying high-risk populations of tuberculosis, and suggest that promoting tea drinking might be a new way to reduce the risk of tuberculosis for individuals with mutations in the four SNPs. |
| Publish Date |
2020-09-28 01:45 |
| Citation |
Wang M, Ma SJ, Wu XY, Zhang X, Abesig J, Xiao ZH, Huang X, Yan HP, Wang J, Chen MS, Tan HZ. Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis. World J Clin Cases 2020; 8(19): 4320-4330
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| URL |
https://www.wjgnet.com/2307-8960/full/v8/i19/4320.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i19.4320 |
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