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Articles Published Processes
1/8/2021 9:54:09 AM | Browse: 569 | Download: 948
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Received |
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2020-06-11 15:50 |
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Peer-Review Started |
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2020-06-11 15:51 |
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To Make the First Decision |
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Return for Revision |
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2020-11-14 02:12 |
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Revised |
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2020-11-23 03:04 |
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Second Decision |
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2020-12-09 09:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-12-10 19:31 |
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Articles in Press |
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2020-12-10 19:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-12-24 01:03 |
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Publish the Manuscript Online |
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2021-01-08 09:54 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
Effect of a fever in viral infections — the ‘Goldilocks’ phenomenon?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lucas Belon, Peter Skidmore, Rohan Mehra and Edward Walter |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Edward Walter, BM BCh, BSc, FRCA, MRCP, N/A, Attending Doctor, Department of Intensive Care Medicine, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, Surrey, United Kingdom. ewalter@nhs.net |
| Key Words |
Fever; Virus; Coronavirus; Infection; Body temperature regulation; Hyperthermia |
| Core Tip |
Acute infections, including those due to coronavirus and other viruses, often stimulate a febrile response. A mild fever appears to improve outcome; it appears to diminish viral replication by several mechanisms, and improve host defence mechanisms against the pathogen. At higher temperatures, the outcome worsens, suggesting that the risks of fever on the host outweigh the benefit. A non-infective fever is associated with a worse outcome at lower temperatures. This paper discusses why a mild fever may be better than no, or very high fever. |
| Publish Date |
2021-01-08 09:54 |
| Citation |
Belon L, Skidmore P, Mehra R, Walter E. Effect of a fever in viral infections — the ‘Goldilocks’ phenomenon? World J Clin Cases 2021; 9(2): 296-307 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i2/296.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i2.296 |
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