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Articles Published Processes
11/26/2020 10:14:32 AM | Browse: 592 | Download: 1292
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Received |
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2020-06-28 07:15 |
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Peer-Review Started |
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2020-06-28 07:16 |
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To Make the First Decision |
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Return for Revision |
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2020-08-09 14:58 |
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Revised |
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2020-08-19 02:21 |
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Second Decision |
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2020-09-10 10:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-09-10 17:45 |
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Articles in Press |
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2020-09-10 17:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-09-25 01:23 |
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Typeset the Manuscript |
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2020-11-25 06:03 |
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Publish the Manuscript Online |
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2020-11-26 10:14 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Review |
Article Title |
Understanding cellular and molecular mechanisms of pathogenesis of diabetic tendinopathy
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Manuscript Source |
Invited Manuscript |
All Author List |
Pan-Pan Lu, Min-Hao Chen, Guang-Chun Dai, Ying-Juan Li, Liu Shi and Yun-Feng Rui |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81572187 |
National Natural Science Foundation of China |
81871812 |
Jiangsu Provincial Medical Talent, The Project of Invigorating Health Care through Science, Technology and Education |
ZDRCA2016083 |
The Six Projects Sponsoring Talent Summits of Jiangsu Province, China |
LGY2017099 |
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Corresponding Author |
Yun-Feng Rui, MD, PhD, Deputy Director, Professor, Department of Orthopaedics, Zhongda Hospital, School of Medicine, Southeast University, No. 87 Ding Jia Qiao, Nanjing 210009, Jiangsu Province, China. ruiyunfeng@126.com |
Key Words |
Tendinopathy; Diabetes; Mechanism; Tenocyte; Tendon stem/progenitor cells; |
Core Tip |
Tendinopathy is an important cause of chronic pain, restricted activity and even tendon rupture in individuals with diabetes. Both tenocytes and tendon stem/progenitor cells (TSPCs) play essential roles in tendon maintenance, regeneration and repair. In this review, we describe the biomechanical properties and histopathological changes in diabetic tendons. Then, we summarize the cellular and molecular alterations and the underlying mechanisms involved in tenocytes and TSPCs that might be associated with the development and progression of diabetic tendinopathy, providing clues for potential effective therapeutics for diabetic tendinopathy. |
Publish Date |
2020-11-26 10:14 |
Citation |
Lu PP, Chen MH, Dai GC, Li YJ, Shi L, Rui YF. Understanding cellular and molecular mechanisms of pathogenesis of diabetic tendinopathy. World J Stem Cells 2020; 12(11): 1255-1275 |
URL |
https://www.wjgnet.com/1948-0210/full/v12/i11/1255.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v12.i11.1255 |
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