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Articles Published Processes
11/12/2020 3:59:23 AM | Browse: 648 | Download: 1159
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Received |
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2020-07-07 10:48 |
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Peer-Review Started |
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2020-07-07 10:48 |
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To Make the First Decision |
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Return for Revision |
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2020-09-17 22:23 |
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Revised |
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2020-09-27 09:49 |
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Second Decision |
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2020-10-16 08:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-10-19 20:18 |
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Articles in Press |
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2020-10-19 20:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-27 01:34 |
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Typeset the Manuscript |
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2020-11-09 06:26 |
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Publish the Manuscript Online |
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2020-11-12 03:59 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Cancer-related microangiopathic hemolytic anemia in patients with advanced gastric cancer: A retrospective single-center analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Anne Katrin Berger, Michael Allgäuer, Leonidas Apostolidis, Anna Elisa Schulze-Schleithoff, Uta Merle, Dirk Jaeger and Georg Martin Haag |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Anne Katrin Berger, MD, Attending Doctor, Department of Medical Oncology, National Center for Tumor Diseases, University Hospital of Heidelberg, Im Neuenheimer Feld 460, Heidelberg 69120, Germany. anne.berger@med.uni-heidelberg.de |
| Key Words |
Microangiopathic hemolytic anemia; Gastric cancer; Chemotherapy; Second-line chemotherapy; Thrombocytopenia; Microsatellite instability-high tumor |
| Core Tip |
Microangiopathic hemolytic anemia (MAHA) with thrombopenia and organ failure caused by tumor-associated thrombotic microangiopathy (TMA) is a rare and life-threatening oncological emergency. The only proven therapy is the treatment of the underlying malignancy. In our retrospective series, 6 of 8 cancer-related (CR)-MAHA patients with advanced gastric cancer received combination chemotherapy with an overall survival (OS) of 10.3 wk. For the whole cohort, OS was only 1.8 wk. Secondline treatment did not show any benefit. One patient with microsatellite instability-high tumor is under immunotherapy for more than 3 years, which to our knowledge is the first reported long-time survival in CR-MAHA patients with advanced disease. |
| Publish Date |
2020-11-12 03:59 |
| Citation |
Berger AK, Allgäuer M, Apostolidis L, Schulze-Schleithoff AE, Merle U, Jaeger D, Haag GM. Cancer-related microangiopathic hemolytic anemia in patients with advanced gastric cancer: A retrospective single-center analysis. World J Gastrointest Oncol 2020; 12(11): 1288-1295 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i11/1288.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i11.1288 |
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