Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Platelet count/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis
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Manuscript Source |
Invited Manuscript |
All Author List |
Alejandro González-Ojeda, Gabino Cervantes-Guevara, Manuela Chávez-Sánchez, Carlos Dávalos-Cobián, Susana Ornelas-Cázares, Michel Dassaejv Macías-Amezcua, Mariana Chávez-Tostado, Kenia Militzi Ramírez-Campos, Anaís del Rocío Ramírez-Arce and Clotilde Fuentes-Orozco |
Funding Agency and Grant Number |
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Corresponding Author |
Clotilde Fuentes-Orozco, MD, PhD, Research Unit in Clinical Epidemiology, Specialties Hospital of the Western Medical Center, Medical Unit of High Specialty, Mexican Institute of Social Security, Avenida Belisario Dominguez 1000, Colonia Independencia, Guadalajara, CP 44340, Jalisco, Mexico. clotilde.fuentes@gmail.com |
Key Words |
Platelet count/spleen diameter ratio; Esophageal varices; Hepatic cirrhosis; Hepatitis C virus; Mexican patients |
Core Tip |
Using noninvasive parameters for high-risk esophageal varices may reduce the need for endoscopies. The ratio of platelet count/diameter of the spleen (PC/SD ratio) is the principal noninvasive predictor of esophageal varices for stratifying patients with cirrhosis. These parameters are easy to obtain, reproducible and noninvasive. In our study, the cutoff point for PC/SD ratio was lower than that reported in previous literature (< 884.3 and < 909, respectively), with a sensitivity of 84% and specificity of 70%. The differences are probably influenced by racial characteristics. The PC/SD ratio should be considered to identifying patients with esophageal varices.
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Publish Date |
2014-02-26 11:18 |
Citation |
González-Ojeda A, Cervantes-Guevara G, Chávez-Sánchez M, Dávalos-Cobián C, Ornelas-Cázares S, Macías-Amezcua MD, Chávez-Tostado M, Ramírez-Campos KM, Ramírez-Arce AR, Fuentes-Orozco C. Platelet count/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis. World J Gastroenterol 2014; 20(8): 2079-2084 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i8/2079.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i8.2079 |