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8/28/2014 3:52:00 PM | Browse: 1136 | Download: 925
Publication Name World Journal of Gastroenterology
Manuscript ID 5850
Country/Territory Canada
Received
2013-09-28 15:50
Peer-Review Started
2013-09-29 12:25
To Make the First Decision
2013-10-14 21:08
Return for Revision
2013-10-16 17:10
Revised
2013-11-13 05:18
Second Decision
2013-12-13 14:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-13 14:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-04-22 17:23
Publish the Manuscript Online
2014-05-07 10:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Vitamin D improves inflammatory bowel disease outcomes: Basic science and clinical review
Manuscript Source Invited Manuscript
All Author List Krista M Reich, Richard N Fedorak, Karen Madsen and Karen I Kroeker
Funding Agency and Grant Number
Funding Agency Grant Number
Center of Excellence for Gastrointestinal to Reich KM
Immunity Research (CEGIIR) to Reich KM
Alberta Innovates-Health Solutions Inflammatory Bowel Disease Consortium to Reich KM
Corresponding Author Karen I Kroeker, MD, FRCPC, Assistant Professor, Division of Gastroenterology, University of Alberta, 2-40 Zeidler Ledcor Centre, 130 University Campus, Edmonton, Alberta T6G 2X8, Canada. karen.kroeker@ualberta.ca
Key Words Vitamin D; Inflammatory bowel disease; Immune response; Inflammation; Cytokines; Supplementation
Core Tip There is support for the importance of maintaining normal vitamin D levels in inflammatory bowel disease (IBD) patients, demonstrated by its anti-inflammatory actions in the gut. A randomized controlled trial examined the impact of vitamin D supplementation on IBD outcomes and demonstrated a reduced risk of relapse in vitamin D-treated Crohn’s disease patients. Furthermore, vitamin D3 and active vitamin D have been shown to reduce clinical disease activity and improve quality of life in IBD patients. Normalization of vitamin D levels is also associated with a decreased risk for IBD-related surgery. This vitamin has therapeutic benefit in IBD patients.
Publish Date 2014-05-07 10:10
Citation Reich KM, Fedorak RN, Madsen K, Kroeker KI. Vitamin D improves inflammatory bowel disease outcomes: Basic science and clinical review. World J Gastroenterol 2014; 20(17): 4934-4947
URL http://www.wjgnet.com/1007-9327/full/v20/i17/4934.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i17.4934
Full Article (PDF) WJG-20-4934.pdf
Full Article (Word) WJG-20-4934.doc
Manuscript File 5850-Review.docx
Answering Reviewers 5850-Answering reviewers.pdf
Copyright License Agreement 5850-Copyright assignment.pdf
Peer-review Report 5850-Peer reviews.pdf
Scientific Editor Work List 5850-Scientific editor work list.doc