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Articles Published Processes
11/13/2020 3:40:10 AM | Browse: 643 | Download: 1450
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Received |
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2020-08-13 14:54 |
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Peer-Review Started |
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2020-08-13 14:55 |
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To Make the First Decision |
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Return for Revision |
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2020-09-16 18:20 |
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Revised |
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2020-09-29 17:53 |
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Second Decision |
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2020-10-16 08:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-19 20:16 |
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Articles in Press |
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2020-10-19 20:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-22 22:41 |
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Typeset the Manuscript |
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2020-11-12 01:34 |
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Publish the Manuscript Online |
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2020-11-13 03:40 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Observational Study |
Article Title |
Glucagon-like-1 receptor agonists and sodium/glucose cotransporter 2 inhibitors combination—are we exploiting their full potential in a real life setting
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Manuscript Source |
Invited Manuscript |
All Author List |
Maja Cigrovski Berkovic, Ines Bilic-Curcic, Tomislav Bozek, Davorka Herman Mahecic, Sanja Klobucar Majanovic, Silvija Canecki-Varzic, Jelena Andric, Srecko Marusic and Anna Mrzljak |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Anna Mrzljak, MD, PhD, Reader (Associate Professor), Department of Medicine, Merkur University Hospital, School of Medicine, University of Zagreb, Zajčeva 19, Zagreb 10000, Croatia. anna.mrzljak@mef.hr |
Key Words |
Sodium/glucose cotransporter 2 inhibitors; Glucagon-like-1 receptor agonists; Type 2 diabetes mellitus; Body weight; Glycemic control; Cardiovascular complications |
Core Tip |
Both glucagon-like-1 receptor agonists and sodium/glucose cotransporter 2 inhibitors when added sequentially to the other or simultaneously decrease the hemoglobin A1c (HbA1c), and reduce the body mass index, but the weight loosing and glucose-lowering potential is not additive in case of their simultaneous use. Half of the patients achieved target HbA1c below 7%, irrespective of treatment group (sequential or simultaneous addition). 5% weight loss was dominantly achieved in the simultaneous therapy group. Composite outcome (reduction of HbA1c below 7% with 5% weight loss) was achieved in 32.3%, while 18.2% of total patients attained composite outcome defined as HbA1c below 7% with 5% weight loss and LDL cholesterol < 2.5 mmol/L. |
Publish Date |
2020-11-13 03:40 |
Citation |
Cigrovski Berkovic M, Bilic-Curcic I, Bozek T, Herman Mahecic D, Klobucar Majanovic S, Canecki-Varzic S, Andric J, Marusic S, Mrzljak A. Glucagon-like-1 receptor agonistsGLP-1RA and sodium/glucose cotransporter 2 inhibitors combination—are we exploiting their full potential in a real life setting. World J Diabetes 2020; 11(11): 540-552 |
URL |
https://www.wjgnet.com/1948-9358/full/v11/i11/540.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v11.i11.540 |
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