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Articles Published Processes
12/4/2020 9:56:58 AM | Browse: 766 | Download: 1496
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Received |
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2020-08-07 16:07 |
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Peer-Review Started |
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2020-08-07 16:08 |
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To Make the First Decision |
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Return for Revision |
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2020-09-24 19:52 |
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Revised |
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2020-09-28 10:53 |
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Second Decision |
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2020-10-16 12:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-20 03:14 |
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Articles in Press |
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2020-10-20 03:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-12-01 07:47 |
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Publish the Manuscript Online |
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2020-12-04 09:56 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
What is the gut feeling telling us about physical activity in colorectal carcinogenesis?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maja Cigrovski Berkovic, Vjekoslav Cigrovski, Ines Bilic-Curcic and Anna Mrzljak |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Anna Mrzljak, MD, PhD, Reader (Associate Professor), Department of Medicine, Merkur University Hospital, Zajceva 19, Zagreb 10000, Croatia. anna.mrzljak@mef.hr |
| Key Words |
Physical activity; Colorectal cancer; Insulin signaling pathway; Inflammation; Gut microbiota; |
| Core Tip |
Sedentary lifestyle is linked to the development of colorectal cancer (CRC); each 2-h increase in sitting time increases the risk of CRC development by 8%. Additionally, engaging in physical activity can prevent 15% of CRC, and by replacing 30 min of sedentary time with physical activity (either light or moderate-vigorous), cancer mortality can be reduced by 8% and 31%, respectively. Although the mechanisms of preventive and favorable effects of physical activity on CRC are still unknown, the most plausible are the influence on chronic inflammation and insulin resistance, with a positive effect on insulin growth factor 1 signaling pathways. |
| Publish Date |
2020-12-04 09:56 |
| Citation |
Cigrovski Berkovic M, Cigrovski V, Bilic-Curcic I, Mrzljak A. What is the gut feeling telling us about physical activity in colorectal carcinogenesis? World J Clin Cases 2020; 8(23): 5844-5851 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i23/5844.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i23.5844 |
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