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11/25/2020 2:44:04 PM | Browse: 348 | Download: 550
Publication Name World Journal of Clinical Cases
Manuscript ID 58773
Country China
Received
2020-08-06 06:39
Peer-Review Started
2020-08-06 06:40
To Make the First Decision
Return for Revision
2020-08-21 04:46
Revised
2020-09-04 06:58
Second Decision
2020-09-17 12:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-17 17:36
Articles in Press
2020-09-17 17:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-09-29 08:00
Typeset the Manuscript
2020-11-13 00:37
Publish the Manuscript Online
2020-11-25 14:44
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Case Report
Article Title Gonadal dysgenesis in Turner syndrome with Y-chromosome mosaicism: Two case reports
Manuscript Source Unsolicited Manuscript
All Author List Xue-Fei Leng, Ke Lei, Yi Li, Fei Tian, Qin Yao, Qing-Mei Zheng and Zhi-Hong Chen
ORCID
Author(s) ORCID Number
Xue-Fei Leng http://orcid.org/0000-0003-0823-4373
Ke Lei http://orcid.org/0000-0002-2523-5530
Yi Li http://orcid.org/0000-0003-1486-6377
Fei Tian http://orcid.org/0000-0003-0266-4364
Qin Yao http://orcid.org/0000-0002-9208-3952
Qing-Mei Zheng http://orcid.org/0000-0003-4454-4686
Zhi-Hong Chen http://orcid.org/0000-0002-2194-2545
Funding Agency and Grant Number
Corresponding Author Zhi-Hong Chen, MD, Chief Doctor, Department of Pediatric Endocrinology, Affiliated Hospital of Medical College Qingdao University, NO. 16 Jiangsu Road, Qingdao 266001, Shandong Province, China. qyczh123@163.com
Key Words Turner syndrome; Gonadal dysgenesis; Virilization; Y chromosome mosaicism; Gonadoblastoma; Case report
Core Tip In this article, we report two cases of Turner syndrome (TS) with different karyotypes and gonadal dysgenesis. The results show the importance of testing at least two to three tissues to search for cryptic Y material in TS patients with virilization. Polymerase chain reaction and FISH analyses can be used for enhanced screening of Y sequences in TS patients. Different tissues in the same TS individual may exhibit different ratios of mosaicism. The gonadal determination and differentiation of mosaic TS are primarily dependent on the predominant cell line in the gonads.
Publish Date 2020-11-25 14:44
Citation Leng XF, Lei K, Li Y, Tian F, Yao Q, Zheng QM, Chen ZH. Gonadal dysgenesis in Turner syndrome with Y-chromosome mosaicism: Two case reports. World J Clin Cases 2020; 8(22): 5737-5743
URL https://www.wjgnet.com/2307-8960/full/v8/i22/5737.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i22.5737
Full Article (PDF) WJCC-8-5737.pdf
Full Article (Word) WJCC-8-5737.docx
Manuscript File 58773-Review-Webster J.docx
Answering Reviewers 58773-Answering reviewers.pdf
Audio Core Tip 58773-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 58773-Conflict-of-interest statement.pdf
Copyright License Agreement 58773-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 58773-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 58773-Language certificate.pdf
Peer-review Report 58773-Peer-review(s).pdf
Scientific Misconduct Check 58773-Scientific misconduct check.pdf
Scientific Editor Work List 58773-Scientific editor work list.pdf