Publication Name	World Journal of Clinical Cases
Manuscript ID	58893
Country	Taiwan

Received	2020-09-07 01:58
Peer-Review Started	2020-09-07 01:59
To Make the First Decision
Return for Revision	2020-09-23 05:40
Revised	2020-09-30 02:57
Second Decision	2020-10-16 13:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-10-20 02:59
Articles in Press	2020-10-20 02:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-11-19 18:04
Publish the Manuscript Online	2020-11-25 14:44

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Clinical Neurology
Manuscript Type	Case Report
Article Title	Amelioration of cognitive impairment following growth hormone replacement therapy: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Jung-Tung Liu and Pen-Hua Su
ORCID	Author(s) ORCID Number Jung-Tung Liu http://orcid.org/0000-0003-1260-0022 Pen-Hua Su http://orcid.org/0000-0001-6627-9364
Funding Agency and Grant Number
Corresponding Author	Pen-Hua Su, MD, PhD, Professor, Department of Pediatrics and Genetics, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo North Road, South District, Taichung 40201, Taiwan. jen@csh.org.tw
Key Words	Cerebral hemorrhage; Growth hormone; Cognitive dysfunction; Case report; ;
Core Tip	We present a case report of a female patient suffered nontraumatic intracerebral hemorrhage and was diagnosed with adult growth hormone deficiency five years later. Unexpected improvements in cognitive function, fluency of speech, and mobility were observed after six months of growth hormone replacement therapy, suggesting that growth hormone replacement therapy may provide further beneficial effects in adult growth hormone deficiency patients with cognitive or motor impairments due to intracerebral hemorrhage.
Publish Date	2020-11-25 14:44
Citation	Liu JT, Su PH. Amelioration of cognitive impairment following growth hormone replacement therapy: A case report and review of literature. World J Clin Cases 2020; 8(22): 5773-5780
URL	https://www.wjgnet.com/2307-960/full/v8/i22/5773.htm
DOI	https://dx.doi.org/10.12998/wjcc.v8.i22.5773

Full Article (PDF)	WJCC-8-5773.pdf
Full Article (Word)	WJCC-8-5773.docx
CARE Checklist–2016	58893-CARE-Checklist–2016-revision.pdf
Manuscript File	58893_Auto_Edited.docx
Answering Reviewers	58893-Answering reviewers.pdf
Audio Core Tip	58893-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	58893-Conflict-of-interest statement.pdf
Copyright License Agreement	58893-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	58893-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	58893-Language certificate.pdf
Peer-review Report	58893-Peer-review(s).pdf
Scientific Misconduct Check	58893-Scientific misconduct check.pdf
Scientific Editor Work List	58893-Scientific editor work list.pdf
CrossCheck Report	58893-CrossCheck report.pdf