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Articles Published Processes
10/14/2020 11:33:23 AM | Browse: 862 | Download: 2040
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Received |
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2020-08-14 22:35 |
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Peer-Review Started |
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2020-08-14 22:35 |
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First Decision by Editorial Office Director |
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2020-08-22 03:45 |
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Return for Revision |
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2020-08-22 03:45 |
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Revised |
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2020-09-03 18:51 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2020-09-16 12:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-09-17 04:49 |
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Articles in Press |
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2020-09-17 04:49 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-10-14 00:53 |
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Publish the Manuscript Online |
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2020-10-14 11:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Molecular mechanisms of viral hepatitis induced hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Simmone D'souza, Keith CK Lau, Carla S Coffin and Trushar R Patel |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Canada Research Chair program |
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| Alberta Innovates Strategic Research Projects |
G2018000880 |
| Calgary Clinical Research Fund Pilot |
CRF18-0704 |
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| Corresponding Author |
Trushar R Patel, PhD, Associate Professor, Department of Chemistry and Biochemistry, Alberta RNA Research and Training Institute, University of Lethbridge, 4401 University Drive West, Lethbridge T1K3M4, AB, Canada. trushar.patel@uleth.ca |
| Key Words |
Chronic viral infection; Hallmarks of cancer; Hepatocellular carcinoma; Hepatitis B virus; Hepatitis C virus; Hepatitis delta virus co-infection |
| Core Tip |
Hepatocellular carcinoma is a dreaded complication of viral infection with hepatitis B virus and/or hepatitis delta virus and hepatitis C virus. Many of the direct and indirect molecular mechanisms used by these viruses to co-opt the liver microenvironment for persistence also disrupt cell cycle pathways. Indirectly, the immune system has a major role in the contribution of hepatocellular carcinoma in the context of viral hepatitis, but direct viral mechanisms also create a pro-tumorigenic environment. |
| Publish Date |
2020-10-14 11:33 |
| Citation |
D'souza S, Lau KC, Coffin CS, Patel TR. Molecular mechanisms of viral hepatitis induced hepatocellular carcinoma. World J Gastroenterol 2020; 26(38): 5759-5783 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i38/5759.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i38.5759 |
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