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Articles Published Processes
9/1/2014 2:51:00 PM | Browse: 1115 | Download: 785
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Received |
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2013-10-03 20:38 |
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Peer-Review Started |
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2013-10-04 16:29 |
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To Make the First Decision |
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2013-10-14 21:06 |
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Return for Revision |
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2013-10-18 09:21 |
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Revised |
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2013-11-15 14:10 |
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Second Decision |
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2014-01-06 18:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-01-06 18:52 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-03-01 15:57 |
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Publish the Manuscript Online |
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2014-03-18 14:14 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Interaction between hepatitis C virus and metabolic factors
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Manuscript Source |
Invited Manuscript |
All Author List |
Yasunori Kawaguchi and Toshihiko Mizuta |
Funding Agency and Grant Number |
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Corresponding Author |
Yasunori Kawaguchi, MD, Department of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan. kawaguy@cc.saga-u.ac.jp |
Key Words |
Hepatitis C virus; Insulin resistance; Diabetes; Lipid metabolism abnormality; Hepatic steatosis; Iron overload; Oxidative stress; Visceral obesity |
Core Tip |
A specific pathophysiologic feature of hepatitis C virus (HCV) infection is whole-body insulin resistance, which is related to oxidative stress, lipid metabolism abnormalities, hepatic steatosis, and iron overload. Host metabolic factors synergistically enhance the HCV-induced metabolic disturbance, affectively deteriorating the clinical course in patients with chronic hepatitis C. Consequently, diet, lifestyle and medications appropriate for metabolic disorders are important for management of HCV-infected patients to improve their prognosis. |
Publish Date |
2014-03-18 14:14 |
Citation |
Kawaguchi Y, Mizuta T. Interaction between hepatitis C virus and metabolic factors. World J Gastroenterol 2014; 20(11): 2888-2901 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i11/2888.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i11.2888 |
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