Publication Name	World Journal of Gastroenterology
Manuscript ID	5907
Country	Japan

Received	2013-10-03 20:38
Peer-Review Started	2013-10-04 16:29
To Make the First Decision	2013-10-14 21:06
Return for Revision	2013-10-18 09:21
Revised	2013-11-15 14:10
Second Decision	2014-01-06 18:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-06 18:52
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-01 15:57
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Interaction between hepatitis C virus and metabolic factors
Manuscript Source	Invited Manuscript
All Author List	Yasunori Kawaguchi and Toshihiko Mizuta
Funding Agency and Grant Number
Corresponding Author	Yasunori Kawaguchi, MD, Department of Internal Medicine, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan. kawaguy@cc.saga-u.ac.jp
Key Words	Hepatitis C virus; Insulin resistance; Diabetes; Lipid metabolism abnormality; Hepatic steatosis; Iron overload; Oxidative stress; Visceral obesity
Core Tip	A specific pathophysiologic feature of hepatitis C virus (HCV) infection is whole-body insulin resistance, which is related to oxidative stress, lipid metabolism abnormalities, hepatic steatosis, and iron overload. Host metabolic factors synergistically enhance the HCV-induced metabolic disturbance, affectively deteriorating the clinical course in patients with chronic hepatitis C. Consequently, diet, lifestyle and medications appropriate for metabolic disorders are important for management of HCV-infected patients to improve their prognosis.
Publish Date	2014-03-18 14:14
Citation	Kawaguchi Y, Mizuta T. Interaction between hepatitis C virus and metabolic factors. World J Gastroenterol 2014; 20(11): 2888-2901
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/2888.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.2888

Full Article (PDF)	WJG-20-2888.pdf
Full Article (Word)	WJG-20-2888.doc
Manuscript File	5907-Review.doc
Answering Reviewers	5907-Answering reviewers.pdf
Copyright License Agreement	5907-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5907-Language certificate.pdf
Peer-review Report	5907-Peer reviews.pdf
Scientific Editor Work List	5907-Scientific editor work list.doc