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Articles Published Processes
9/3/2014 2:27:00 PM | Browse: 1134 | Download: 1029
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Received |
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2013-09-28 20:13 |
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Peer-Review Started |
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2013-09-30 10:20 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-10-23 12:17 |
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Revised |
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2013-11-09 12:24 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-12-13 14:03 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-12-13 14:58 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-16 11:24 |
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Publish the Manuscript Online |
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2014-02-20 19:40 |
| Category |
Microbiology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Campylobacter concisus and inflammatory bowel disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Li Zhang, Hoyul Lee, Michael C Grimm, Stephen M Riordan, Andrew S Day and Daniel A Lemberg |
| Funding Agency and Grant Number |
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| Corresponding Author |
Li Zhang, MBBS, PhD, Senior Lecturer (Medical Microbiology and Immunology), School of Biotechnology and Biomolecular Sciences, University of New South Wales, High St, Kensington, Sydney, NSW 2052, Australia. l.zhang@unsw.edu.au |
| Key Words |
Campylobacter concisus; Inflammatory bowel disease; Zonula occludens toxin; Tight junctions; Intestinal permeability |
| Core Tip |
Campylobacter concisus (C. concisus) is an oral bacterium that was previously shown to be associated with inflammatory bowel disease (IBD). Evidence presented in this review shows that some strains of C. concisus acquired zonula occludens toxin (zot) gene from a virus (prophage), suggesting that a primary barrier function defect caused by C. concisus Zot is a mechanism by which zot-positive C. concisus strains may trigger the onset and relapse of IBD. |
| Publish Date |
2014-02-20 19:40 |
| Citation |
Zhang L, Lee H, Grimm MC, Riordan SM, Day AS, Lemberg DA. Campylobacter concisus and inflammatory bowel disease. World J Gastroenterol 2014; 20(5): 1259-1267 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i5/1259.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i5.1259 |
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