Publication Name	World Journal of Gastroenterology
Manuscript ID	5924
Country	Italy

Received	2013-09-28 20:54
Peer-Review Started	2013-09-30 10:57
To Make the First Decision	2013-12-26 10:52
Return for Revision	2013-12-30 16:53
Revised	2014-02-17 20:38
Second Decision	2014-05-14 09:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 09:42
Articles in Press	2014-05-23 10:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-30 17:24
Publish the Manuscript Online	2014-09-18 19:50

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Retrospective Study
Article Title	Impact of immunosuppression minimization and withdrawal in long-term hepatitis C virus liver transplant recipients
Manuscript Source	Invited Manuscript
All Author List	Tommaso Maria Manzia, Roberta Angelico, Paolo Ciano, Jon Mugweru, Kofi Owusu, Daniele Sforza, Luca Toti and Giuseppe Tisone
Funding Agency and Grant Number
Corresponding Author	Tommaso Maria Manzia, MD, PhD, Department of Experimental Medicine and Surgery, Section of Transplantation, Tor Vergata University of Rome, Viale Oxford 81, 00133 Rome, Italy. tomanzia@libero.it
Key Words	Liver transplantation; Hepatitis C virus recurrence; Immunosuppression withdrawal; Micofenolate mofetil; Clinical operational tolerance; Minimization of immunosuppression
Core Tip	The ideal immunosuppression (IS) therapy in long term hepatitis C virus (HCV) transplant recipients is yet to be defined but over-immunosuppression should be avoided. The IS free status seems to show a favorable impact on the natural history of the disease but is only achievable in 20%-30% of liver transplant (LT) recipients. Therefore minimization of the therapy must be considered an alternative in those patients who require IS. The present study aims to compare the fibrosis progression in long-term IS-free HCV-LT recipients with those on low dose calcineurin inhibitors or on antimetabolite.
Publish Date	2014-09-18 19:50
Citation	Manzia TM, Angelico R, Ciano P, Mugweru J, Owusu K, Sforza D, Toti L, Tisone G. Impact of immunosuppression minimization and withdrawal in long-term hepatitis C virus liver transplant recipients. World J Gastroenterol 2014; 20(34): 12217-12225
URL	http://www.wjgnet.com/1007-9327/full/v20/i34/12217.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i34.12217

Full Article (PDF)	WJG-20-12217.pdf
Full Article (Word)	WJG-20-12217.doc
Manuscript File	5924-Review.docx
Answering Reviewers	5924-Answering reviewers.pdf
Copyright License Agreement	5924-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5924-Language certificate.pdf
Peer-review Report	5924-Peer reviews.pdf
Scientific Editor Work List	5924-Scientific editor work list.pdf