ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Obstetrics & Gynecology |
Manuscript Type |
Case Control Study |
Article Title |
New indicators in evaluation of hemolysis, elevated liver enzymes, and low platelet syndrome: A case-control study
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Su-Ya Kang, Yun Wang, Li-Ping Zhou and Hong Zhang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
People’s Well-being Project of Suzhou City |
SS201710 |
Clinical Expert Team Introduction Project of Suzhou City |
SZYJTD201709 |
Research Project on Maternal and Child Health of Jiangsu Province |
F202045 |
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Corresponding Author |
Li-Ping Zhou, BSc, Doctor, Doctor, Department of Obstetrics, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, No. 206 Daoqian Street, Gusu District, Suzhou 215002, Jiangsu Province, China. zhoulpszslyy@163.com |
Key Words |
Hemolysis, elevated liver enzymes, and low platelet syndrome; Neutrophil-to-lymphocyte ratio; Platelet-to-lymphocyte ratio; Mean platelet volume; Platelet distribution width; Red cell distribution width |
Core Tip |
Systemic inflammatory response (SIR) markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), platelet distribution width (PDW) and red cell distribution width (RDW), have been widely investigated in preeclampsia (PE) and less analyzed in hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. In this retrospective case-control study, SIR markers were compared among HELLP/PE patients and healthy gravidae. It revealed that NLR, RDW, MPV and PDW were increased and PLR was decreased in HELLP syndrome. These parameters may become predictive and prognostic indicators even useful additions to the current diagnostic standard of HELLP syndrome, if confirmed by further more studies. |
Publish Date |
2021-02-06 11:08 |
Citation |
Kang SY, Wang Y, Zhou LP, Zhang H. New indicators in evaluation of hemolysis, elevated liver enzymes, and low platelet syndrome: A case-control study. World J Clin Cases 2021; 9(6): 1259-1270 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i6/1259.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i6.1259 |