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Articles Published Processes
3/20/2021 2:13:53 AM | Browse: 688 | Download: 1611
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Received |
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2020-10-23 14:54 |
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Peer-Review Started |
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2020-10-23 14:55 |
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To Make the First Decision |
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Return for Revision |
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2020-11-30 02:30 |
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Revised |
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2020-12-30 14:09 |
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Second Decision |
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2021-01-25 06:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-02-12 05:07 |
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Articles in Press |
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2021-02-12 05:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-02-16 23:33 |
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Typeset the Manuscript |
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2021-03-01 01:11 |
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Publish the Manuscript Online |
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2021-03-20 02:13 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nutrition & Dietetics |
| Manuscript Type |
Basic Study |
| Article Title |
Papaya improves nonalcoholic fatty liver disease in obese rats by attenuating oxidative stress, inflammation and lipogenic gene expression
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wanwisa Deenin, Wachirawadee Malakul, Tantip Boonsong, Ittipon Phoungpetchara and Sakara Tunsophon |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Research Council of Thailand |
S.T., R2560B137 |
| National Research Council of Thailand |
W.D., 2562/20 |
| Thailand Research Fund |
S.T., RDG5820017 |
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| Corresponding Author |
Sakara Tunsophon, PhD, Assistant Professor, Department of Physiology, Faculty of Medical Science, Naresuan University, 99 Moo 9 TahPoh, Muang 65000, Phitsanulok, Thailand. sakarat@nu.ac.th |
| Key Words |
High fat diet; Lipogenic gene expression; Non-alcoholic fatty liver disease; Obesity; Oxidative stress; Papaya |
| Core Tip |
High fat diet consumption causes nonalcoholic fatty liver disease (NAFLD). This is one of the major liver diseases found worldwide. Liver fat accumulation leads to dysfunction of liver due to oxidative stress and inflammation. Papaya is an important export fruit from Asian and Latin America. It is a nutrient rich fruit with many medicinal properties. Our present study clearly demonstrated the hepatoprotective mechanism of papaya against NAFLD was a result of the association of the hypolipidemic, anti-inflammatory and antioxidant activities. This study provides evidence for the beneficial effects of papaya to reverse the progression of NAFLD in obese rats. |
| Publish Date |
2021-03-20 02:13 |
| Citation |
Deenin W, Malakul W, Boonsong T, Phoungpetchara I, Tunsophon S. Papaya improves nonalcoholic fatty liver disease in obese rats by attenuating oxidative stress, inflammation and lipogenic gene expression. World J Hepatol 2021; 13(3): 315-327 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i3/315.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i3.315 |
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