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12/25/2020 10:20:16 AM | Browse: 1229 | Download: 1997
Publication Name World Journal of Gastroenterology
Manuscript ID 60211
Country United States
Received
2020-10-20 15:26
Peer-Review Started
2020-10-20 15:27
First Decision by Editorial Office Director
2020-11-13 16:52
Return for Revision
2020-11-13 16:52
Revised
2020-11-24 15:37
Publication Fee Transferred
Second Decision by Editor
2020-12-04 12:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2020-12-06 01:46
Articles in Press
2020-12-06 01:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-12-23 04:22
Publish the Manuscript Online
2020-12-25 10:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Gut microbiota mediated molecular events and therapy in liver diseases
Manuscript Source Invited Manuscript
All Author List Xiaoqiang Qi, Ming Yang, Joseph Stenberg, Rahul Dey, Leslie Fogwe, Muhammad Shawkat Alam, Eric T Kimchi, Kevin F Staveley-O'Carroll and Guangfu Li
ORCID
Author(s) ORCID Number
Xiaoqiang Qi http://orcid.org/0000-0002-5631-4362
Ming Yang http://orcid.org/0000-0002-4895-5864
Joseph Stenberg http://orcid.org/0000-0003-4435-0240
Rahul Dey http://orcid.org/0000-0003-3882-4251
Leslie Fogwe http://orcid.org/0000-0001-9869-3375
Muhammad Shawkat Alam http://orcid.org/0000-0002-1227-1305
Eric T Kimchi http://orcid.org/0000-0002-5046-1142
Kevin F Staveley-O'Carroll http://orcid.org/0000-0003-2207-0379
Guangfu Li http://orcid.org/0000-0002-9817-568X
Funding Agency and Grant Number
Funding Agency Grant Number
NIH Grant R01CA208396
VA Merit Award I01 BX004065-1
Corresponding Author Guangfu Li, DVM, PhD, Assistant Professor, Department of Surgery, University of Missouri, 230 Jesse Hall, Columbia, MO 65212, United States. liguan@health.missouri.edu
Key Words Gut microbiota; Intrahepatic immunity; Metabolite; Fecal microbial transplantation; Probiotic; Antibiotic
Core Tip Accumulating evidence shows that gut microbiota plays a critical role in liver pathophysiology and targeting gut microbiota is a potential treatment option for chronic liver disease. Herein, this review explores the cellular and molecular mechanisms of how gut microbiota contributes to liver diseases, including alcohol-induced and nonalcohol-induced liver fatty liver diseases, liver fibrosis, cirrhosis, and cancer. This review also summarizes the current gut microbiota-based therapeutic strategies and discusses future directions in promoting gut microbiota-based therapy for liver diseases.
Publish Date 2020-12-25 10:20
Citation Qi X, Yang M, Stenberg J, Dey R, Fogwe L, Alam MS, Kimchi ET, Staveley-O'Carroll KF, Li G. Gut microbiota mediated molecular events and therapy in liver diseases. World J Gastroenterol 2020; 26(48): 7603-7618
URL https://www.wjgnet.com/1007-9327/full/v26/i48/7603.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i48.7603
Full Article (PDF) WJG-26-7603.pdf
Full Article (Word) WJG-26-7603.docx