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Articles Published Processes
1/30/2021 10:10:27 AM | Browse: 646 | Download: 2097
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Received |
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2020-11-10 11:33 |
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Peer-Review Started |
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2020-11-10 11:36 |
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First Decision by Editorial Office Director |
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2020-11-29 19:23 |
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Return for Revision |
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2020-11-29 19:23 |
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Revised |
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2020-12-12 03:15 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2020-12-22 13:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-12-23 21:09 |
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Articles in Press |
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2020-12-23 21:09 |
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Edit the Manuscript by Language Editor |
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2020-12-31 22:41 |
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Typeset the Manuscript |
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2021-01-25 03:04 |
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Publish the Manuscript Online |
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2021-01-30 10:10 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Respiratory System |
| Manuscript Type |
Case Control Study |
| Article Title |
Serum neuron-specific enolase: A promising biomarker of silicosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Bo Huang, Jun-Ling Huang, Xiao-Ting Xu, Kun-Bo Huang, Yi-Jian Lin, Jie-Bin Lin and Xi-Bin Zhuang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Quanzhou Science and Technology Bureau |
2018N053S |
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| Corresponding Author |
Jun-Ling Huang, MD, Attending Doctor, Department of Pulmonary and Critical Care Medicine, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248-252 East Street, Quanzhou 362000, Fujian Province, China. 236992065@qq.com |
| Key Words |
Silicosis; Neuron-specific enolase; Receiver operating characteristic curve; Disease stage; Biomarker; Diagnosis |
| Core Tip |
The purpose of this study was to investigate the clinical significance of serum neuron-specific enolase (NSE) in the diagnosis and staging of silicosis. The results showed that the serum NSE concentration of silicosis patients was significantly higher than that of non-silicosis patients. With the progression of silicosis, NSE concentration increased gradually. The Receiver operating characteristic curve suggested that when the diagnostic threshold of NSE was 15.82 ng/mL, the area under the curve was 0.858 (P = 0.000), with sensitivity of 72% and specificity of 90%. To the best of our knowledge, this study is the largest study on silicosis biomarkers so far. |
| Publish Date |
2021-01-30 10:10 |
| Citation |
Huang HB, Huang JL, Xu XT, Huang KB, Lin YJ, Lin JB, Zhuang XB. Serum neuron-specific enolase: A promising biomarker of silicosis. World J Clin Cases 2021; 9(5): 1016-1025 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i5/1016.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i5.1016 |
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