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3/5/2021 12:08:55 PM | Browse: 500 | Download: 810
Publication Name World Journal of Clinical Cases
Manuscript ID 60592
Country China
Received
2020-11-05 08:34
Peer-Review Started
2020-11-05 08:34
To Make the First Decision
Return for Revision
2020-12-24 17:40
Revised
2020-12-30 10:30
Second Decision
2021-01-22 12:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-01-23 03:06
Articles in Press
2021-01-23 03:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-02-02 02:53
Typeset the Manuscript
2021-02-14 02:28
Publish the Manuscript Online
2021-03-05 12:08
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Case Report
Article Title Human parvovirus B19-associated early postoperative acquired pure red cell aplasia in simultaneous pancreas-kidney transplantation: A case report
Manuscript Source Unsolicited Manuscript
All Author List Hui Wang, Yingxin Fu, Wen-Li Song, Zhen Wang, Gang Feng, Jie Zhao, Ye-Qi Nian and Yu Cao
ORCID
Author(s) ORCID Number
Hui Wang http://orcid.org/0000-0002-6081-3834
Yingxin Fu http://orcid.org/0000-0001-8010-224X
Wen-Li Song http://orcid.org/0000-0001-6286-2704
Zhen Wang http://orcid.org/0000-0002-7746-8408
Gang Feng http://orcid.org/0000-0002-1627-372X
Jie Zhao http://orcid.org/0000-0002-6450-5046
Ye-Qi Nian http://orcid.org/0000-0002-7479-5307
Yu Cao http://orcid.org/0000-0002-1864-1784
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81970654
Corresponding Author Yingxin Fu, MD, PhD, Chief Doctor, Doctor, Professor, Surgeon, Department of kidney Transplantation, Tianjin First Central Hospital, No. 24, Fukang Road, Nankai District, Tianjin 300192, China. fuyingxintj@163.com
Key Words Anemia; Human parvovirus B19; Intravenous immunoglobulin; Metagenomic; Next-generation sequencing; Pancreas transplantation; Case report
Core Tip This study presents a patient experiencing human parvovirus (HPV) B19-associated acquired pure red cell aplasia (aPRCA) in the early postoperative period with simultaneous pancreas-kidney transplantation. The metagenomic next-generation sequencing (mNGS) testing was used for diagnosing HPV B19 infection and the diminution trend of the mNGS readings was correlated with hemoglobin and reticulocyte count improvements. The effective therapy included intravenous immunoglobulin infusion and adjustment of the immunosuppressive program. HPV B19-associated aPRCA should be considered when a patient experiences erythropoietin-resistant anemia and reticulocytopenia in the early postoperative period. Moreover, mNGS could be used for diagnosis and reflecting disease progression.
Publish Date 2021-03-05 12:08
Citation Wang H, Fu YX, Song WL, Wang Z, Feng G, Zhao J, Nian YQ, Cao Y. Human parvovirus B19-associated early postoperative acquired pure red cell aplasia in simultaneous pancreas-kidney transplantation: A case report. World J Clin Cases 2021; 9(8): 1968-1975
URL https://www.wjgnet.com/2307-8960/full/v9/i8/1968.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i8.1968
Full Article (PDF) WJCC-9-1968.pdf
Full Article (Word) WJCC-9-1968.docx
CARE Checklist–2016 60592-CARE-Checklist–2016-revision.pdf
Manuscript File 60592_Auto_Edited_LM-Webster J-Clear.docx
Answering Reviewers 60592-Answering reviewers.pdf
Audio Core Tip 60592-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 60592-Conflict-of-interest statement.pdf
Copyright License Agreement 60592-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 60592-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 60592-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 60592-Language certificate.pdf
Peer-review Report 60592-Peer-review(s).pdf
Scientific Misconduct Check 60592-Scientific misconduct check.pdf
Scientific Editor Work List 60592-Scientific editor work list.pdf