| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Case Report |
| Article Title |
Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and review of literature
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dimitrios T Papadimitriou, Christina Bothou, Eleni Dermitzaki, Alexios Alexopoulos and George Mastorakos |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Dimitrios T Papadimitriou, MD, MSc, PhD, Academic Fellow, Director, Pediatric-Adolescent Endocrinology and Diabetes, Athens Medical Center, 58, Kifisias av., Athens 15125, Greece. info@pedoendo.net |
| Key Words |
Alopecia totalis; Alopecia universalis; Alopecia focalis; Calcitriol; Paricalcitol; Vitamin D; Case report |
| Core Tip |
Alopecia areata (AA) is an inflammatory disease with autoimmune, environmental, and inherited components directed at the hair follicle, either limited to patchy hair loss over the scalp (Focalis, AF), or as total loss of scalp hair (Totalis, AT) or as total loss of both scalp and body hair (Universalis, AU). Despite multiple treatment modalities, no therapy still stands. Three girls aged 3, 7 and 5 years with AT, AU and AF were treated with oral calcitriol, paricalcitol and cholecalciferol, showing hair regrowth at 6, 6 and 3 mo, respectively, but only at the fur level for P2 with AU. Vitamin D may have an immunomodulating therapeutic impact in AT/AU/AF which needs to be explored with further pilot clinical trials testing the effectiveness and establishing the optimal form and dosage of vitamin D. |
| Publish Date |
2021-11-09 07:27 |
| Citation |
Papadimitriou DT, Bothou C, Dermitzaki E, Alexopoulos A, Mastorakos G. Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and a literature review. World J Clin Pediatr 2021; 10(6): 192-199 |
| URL |
https://www.wjgnet.com/2219-2808/full/v10/i6/192.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v10.i6.192 |
