ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Case Report |
Article Title |
Primary bone anaplastic lymphoma kinase positive anaplastic large-cell lymphoma: A case report and review of literature
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Wei Zheng, Qiao-Qiao Yin, Tian-Chen Hui, Wen-Hao Wu, Qing-Qing Wu, Hai-Jun Huang, Mei-Juan Chen, Rong Yan, Yi-Cheng Huang and Hong-Ying Pan |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Science and Technology Major Subproject of China |
2018ZX10302205-002 |
Chinese Foundation for Hepatitis Prevention and Control-Tianqing Liver Disease Research Fund Subject |
TQGB2020168 |
|
Corresponding Author |
Hong-Ying Pan, MD, Doctor, Doctor, Department of Infectious Diseases, Zhejiang Provincial People’s Hospital People’s Hospital of Hangzhou Medical College, No. 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China. hypanhz@139.com |
Key Words |
Anaplastic large cell lymphoma; Anaplastic lymphoma kinase; Primary bone lymphoma; Bone involvement; Osteolysis; Case report |
Core Tip |
Primary bone lymphoma (PBL) is an uncommon extranodal disease that represents approximately 1%-3% of lymphomas. Among PBLs, diffuse large B-cell lymphoma is the most common pathological type, accounting for approximately 70%-80% of all PBLs. The anaplastic large-cell lymphoma (ALCL) subtype of PBL is extremely rare, and it therefore remains unclear whether it is similar to ALCL in general or whether it is a subtype with unique clinical biological characteristics. Furthermore, the prognostic impact of anaplastic lymphoma kinase (ALK) expression in ALCL with primary bone lesions is still under debate. Herein, we report one rare case of primary bone ALK positive ALCL in a 66-year-old male. This suggested that physicians should keep in mind that ALCL can present with isolated osseous involvement without nodal involvement, and lymphoma should be considered in the differential diagnosis of primary bone lesions. |
Publish Date |
2021-04-29 08:35 |
Citation |
Zheng W, Yin QQ, Hui TC, Wu WH, Wu QQ, Huang HJ, Chen MJ, Yan R, Huang YC, Pan HY. Primary bone anaplastic lymphoma kinase positive anaplastic large-cell lymphoma: A case report and review of literature. World J Clin Cases 2021; 9(14): 3403-3410 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i14/3403.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i14.3403 |