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Articles Published Processes
3/25/2021 6:36:58 AM | Browse: 561 | Download: 1126
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Received |
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2020-11-18 20:40 |
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Peer-Review Started |
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2020-11-18 20:41 |
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To Make the First Decision |
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Return for Revision |
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2021-01-25 18:47 |
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Revised |
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2021-02-07 19:04 |
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Second Decision |
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2021-03-10 07:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-03-11 03:15 |
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Articles in Press |
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2021-03-11 03:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-24 06:13 |
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Publish the Manuscript Online |
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2021-03-25 06:36 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Developmental Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Insulin resistance in diabetes: The promise of using induced pluripotent stem cell technology
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ahmed K Elsayed, Selvaraj Vimalraj, Manjula Nandakumar and Essam M Abdelalim |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Qatar National Research Fund |
NPRP10-1221-160041 |
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| Corresponding Author |
Essam M Abdelalim, DVM, MSc, PhD, Professor, Diabetes Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, Al Rayyan, Doha 34110, Qatar. emohamed@hbku.edu.qa |
| Key Words |
Type 2 diabetes; Insulin target tissues; Human pluripotent stem cells; Induced pluripotent stem cells; Genetic factors; Disease modeling |
| Core Tip |
The genetic factors involved in the development of insulin resistance (IR), associated with type 2 diabetes remains largely unknown due to the polygenic nature of IR and lack of the appropriate human model. In this review, we summarize and discuss the use of human pluripotent stem cell technology in studying the genetic defects underlying IR development as well as highlight the potential use of patient-derived pluripotent stem cell for in vitro IR modeling. |
| Publish Date |
2021-03-25 06:36 |
| Citation |
Elsayed AK, Vimalraj S, Nandakumar M, Abdelalim EM. Insulin resistance in diabetes: The promise of using induced pluripotent stem cell technology. World J Stem Cells 2021; 13(3): 221-235 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i3/221.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i3.221 |
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