Publication Name	World Journal of Gastroenterology
Manuscript ID	6101
Country	Italy

Received	2013-10-02 10:38
Peer-Review Started	2013-10-02 20:38
To Make the First Decision	2013-12-26 11:07
Return for Revision	2013-12-27 21:15
Revised	2014-01-15 00:03
Second Decision	2014-03-10 13:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-10 17:22
Articles in Press	2014-05-23 10:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-25 14:22
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Modern approach to the clinical management of non-alcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Maria Del Ben, Licia Polimeni, Francesco Baratta, Daniele Pastori, Lorenzo Loffredo and Francesco Angelico
Funding Agency and Grant Number
Corresponding Author	Francesco Angelico, MD, Professor of Internal Medicine, Department of Public Health and Infectious Diseases, Sapienza University, 155 viale del Policlinico, 00161 Rome, Italy. francesco.angelico@uniroma1.it
Key Words	Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Insulin resistance; Oxidative stress; Cardiovascular risk; Statins; Vitamin D; Vitamin E; Pioglitazone
Core Tip	Management of fatty liver has become a major challenge to healthcare systems as the consequence of the increasing rates of obesity worldwide. Several therapeutic interventions have been proposed, which include moderate weight loss, insulin sensitizer agents, lipid lowering drugs, antioxidants such as vitamin E and treatment of vitamin D3 deficiency. However, therapeutic approaches have been largely empirical and experimental trials have mostly been carried out in uncontrolled settings with small sample sizes so far. Treatment of coexisting metabolic conditions should be regarded as of paramount importance in the management of these patients.
Publish Date	2014-07-14 17:39
Citation	Del Ben M, Polimeni L, Baratta F, Pastori D, Loffredo L, Angelico F. Modern approach to the clinical management of non-alcoholic fatty liver disease. World J Gastroenterol 2014; 20(26): 8341-8350
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8341.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8341

Full Article (PDF)	WJG-20-8341.pdf
Full Article (Word)	WJG-20-8341.doc
Manuscript File	6101-Peer review(s).pdf
Answering Reviewers	6101-Answering reviewers.pdf
Copyright License Agreement	6101-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6101-Language certificate.pdf
Peer-review Report	6101-Peer review(s).pdf
Scientific Editor Work List	6101-Scientific editor work list.doc