Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	6140
Country	United States

Received	2013-10-04 21:15
Peer-Review Started	2013-10-05 14:07
To Make the First Decision	2013-11-04 14:49
Return for Revision	2013-11-05 19:52
Revised	2013-11-26 22:27
Second Decision	2013-12-19 13:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-19 13:25
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-14 15:45
Publish the Manuscript Online	2014-01-15 10:25

ISSN	1948-5204 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biology
Manuscript Type	Review
Article Title	Approaches that ascertain the role of dietary compounds in colonic cancer cells
Manuscript Source	Invited Manuscript
All Author List	Michael Bordonaro, Koen Venema, Adeline K Putri and Darina Lazarova
Funding Agency and Grant Number	Funding Agency Grant Number NIH grants Acknowledges the Support of the European Science Foundation R15CA152852-01 European Network for Gastrointestinal Health Research R15CA149589-01
Corresponding Author	Darina Lazarova, PhD, Associate Professor, Department of Basic Sciences, The Commonwealth Medical College, 525 Pine Street, Scranton, PA 18509, United States. dlazarova@tcmedc.org
Key Words	Human colon model; Fecal water; Diet; Colon cancer; Prevention; Butyrate; Polyphenols; WNT signaling
Core Tip	Studies on diet and colorectal cancer are in their infancy, and the relevance of many publications on the topic is questionable due to three problems: (1) there is uncertainty about which diet-derived compounds are present in the colon; (2) most studies have focused on individual bioactives; whereas, food intake results in complex metabolite mixtures; and (3) the physiological concentrations of many colonic bioactives are unknown. Here we discuss how the use of fecal water samples and in vitro models of human colon address these problems.
Publish Date	2014-01-15 10:25
Citation	Bordonaro M, Venema K, Putri AK, Lazarova DL. Approaches that ascertain the role of dietary compounds in colonic cancer cells. World J Gastrointest Oncol 2014; 6(1): 1-10
URL	http://www.wjgnet.com/1948-5204/full/v6/i1/1.htm
DOI	http://dx.doi.org/10.4251/wjgo.v6.i1.1

Manuscript File	6140-Review.docx
Answering Reviewers	6140-Answering reviewers.pdf
Copyright License Agreement	6140-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6140-Language certificate.pdf
Peer-review Report	6140-Peer review(s).pdf
Scientific Editor Work List	6140-Scientific editor work list.doc