Publication Name	World Journal of Critical Care Medicine
Manuscript ID	61421
Country	Singapore

Received	2020-12-06 10:49
Peer-Review Started	2020-12-06 10:50
To Make the First Decision
Return for Revision	2020-12-31 04:39
Revised	2021-01-01 08:29
Second Decision	2021-01-06 03:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-01-28 19:19
Articles in Press	2021-01-28 19:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-02-24 03:26
Publish the Manuscript Online	2021-03-01 03:50

ISSN	2220-3141(online)
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Category	Medicine, General & Internal
Manuscript Type	Minireviews
Article Title	Acute cor pulmonale in patients with acute respiratory distress syndrome: A comprehensive review
Manuscript Source	Invited Manuscript
All Author List	Kay Choong See
ORCID	Author(s) ORCID Number Kay Choong See http://orcid.org/0000000325287282
Funding Agency and Grant Number
Corresponding Author	Kay Choong See, FCCP, FRCP, MBBS, MRCP, Doctor, Doctor, Department of Medicine, National University Hospital, 1E Kent Ridge Rd, NUHS Tower Block Level 10, Singapore 119228, Singapore. kay_choong_see@nuhs.edu.sg
Key Words	Coronavirus; Critical care; Echocardiography; Hypertension; Pulmonary; Respiratory distress syndrome; Adult; Ventricular dysfunction; Right
Core Tip	Acute respiratory distress syndrome (ARDS)-related acute cor pulmonale (ACP) is associated with adverse hemodynamic and survival outcomes. It is an echocardiographic diagnosis marked by combined right ventricular dilatation and septal dyskinesia. Checking for ARDS-related ACP should be done in patients with ≥ 2 of 4 risk factors: pneumonia, arterial partial pressure of oxygen-to-inspired oxygen fraction ratio < 150 mmHg, arterial partial pressure of carbon dioxide ≥ 48 mmHg, and driving pressure ≥ 18 cmH2O. Treatments include ventilator adjustment (aiming for arterial partial pressure of carbon dioxide < 60 mmHg, plateau pressure < 27 cmH2O, driving pressure < 17 cmH2O), prone positioning, fluid balance optimization and pharmacotherapy.
Publish Date	2021-03-01 03:50
Citation	See KC. Acute cor pulmonale in patients with acute respiratory distress syndrome: A comprehensive review. World J Crit Care Med 2021; 10(2): 35-42
URL	https://www.wjgnet.com/2220-3141/full/v10/i2/35.htm
DOI	https://dx.doi.org/10.5492/wjccm.v10.i2.35

Full Article (PDF)	WJCCM-10-35.pdf
Full Article (Word)	WJCCM-10-35.docx
Manuscript File	61421_Auto_Edited_LM.docx
Answering Reviewers	61421-Answering reviewers.pdf
Audio Core Tip	61421-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	61421-Conflict-of-interest statement.pdf
Copyright License Agreement	61421-Copyright license agreement.pdf
Peer-review Report	61421-Peer-review(s).pdf
Scientific Misconduct Check	61421-Scientific misconduct check.pdf
Scientific Editor Work List	61421-Scientific editor work list.pdf
CrossCheck Report	61421-CrossCheck report.pdf