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Articles Published Processes
6/23/2021 1:49:40 AM | Browse: 736 | Download: 1121
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Received |
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2021-01-25 21:11 |
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Peer-Review Started |
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2021-01-08 15:24 |
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To Make the First Decision |
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Return for Revision |
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2021-03-29 16:51 |
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Revised |
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2021-04-12 21:38 |
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Second Decision |
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2021-05-21 10:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-21 12:18 |
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Articles in Press |
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2021-05-21 12:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-06-02 02:38 |
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Publish the Manuscript Online |
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2021-06-23 01:49 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Impact of donor-specific antibodies on long-term graft survival with pediatric liver transplantation
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Manuscript Source |
Invited Manuscript |
All Author List |
Felicitas Leonie Schotters, Jan Beime, Andrea Briem-Richter, Thomas Binder, Uta Herden and Enke Freya Grabhorn |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Enke Freya Grabhorn, MD, Attending Doctor, Department of pediatric hepatology and liver transplantatioDepartment of Pediatric Hepatology and Liver Transplantation, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, Hamburg 20246, Germany. egrabhorn@uke.de |
Key Words |
Donor-specific antibodies; Graft rejection; Liver transplantation; Fluoroimmunoassay; Pediatrics; Graft dysfunction; Fibrosis |
Core Tip |
This was a retrospective study to evaluate the impact of donor-specific antibodies (DSAs) on graft survival with pediatric liver transplantation. Graft fibrosis and graft loss was significantly higher in patients with DSAs. Screening for DSAs should be included in follow-ups to avoid delayed identification of patients at risk of graft loss (rejection), and may be even more relevant for patients with early histological signs of possible allograft dysfunction (fibrosis). Moreover, patients with DSAs may be poor candidates for reduction of initial immunosuppression or even weaning. |
Publish Date |
2021-06-23 01:49 |
Citation |
Schotters FL, Beime J, Briem-Richter A, Binder T, Herden U, Grabhorn EF. Impact of donor-specific antibodies on long-term graft survival with pediatric liver transplantation. World J Hepatol 2021; 13(6): 673-685 |
URL |
https://www.wjgnet.com/1948-5182/full/v13/i6/673.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v13.i6.673 |
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