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6/23/2021 1:49:40 AM | Browse: 583 | Download: 666
Publication Name World Journal of Hepatology
Manuscript ID 61431
Country Germany
Received
2021-01-25 21:11
Peer-Review Started
2021-01-08 15:24
To Make the First Decision
Return for Revision
2021-03-29 16:51
Revised
2021-04-12 21:38
Second Decision
2021-05-21 10:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-21 12:18
Articles in Press
2021-05-21 12:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-06-02 02:38
Publish the Manuscript Online
2021-06-23 01:49
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Impact of donor-specific antibodies on long-term graft survival with pediatric liver transplantation
Manuscript Source Invited Manuscript
All Author List Felicitas Leonie Schotters, Jan Beime, Andrea Briem-Richter, Thomas Binder, Uta Herden and Enke Freya Grabhorn
ORCID
Author(s) ORCID Number
Felicitas Leonie Schotters http://orcid.org/0000-0003-0624-9678
Jan Beime http://orcid.org/0000-0001-9397-8208
Andrea Briem-Richter http://orcid.org/0000-0003 4030-2524
Thomas Binder http://orcid.org/0000-0002-5285-2630
Uta Herden http://orcid.org/0000-0003-2921-7943
Enke Freya Grabhorn http://orcid.org/0000-0003-3422-0389
Funding Agency and Grant Number
Corresponding Author Enke Freya Grabhorn, MD, Attending Doctor, Department of pediatric hepatology and liver transplantatioDepartment of Pediatric Hepatology and Liver Transplantation, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, Hamburg 20246, Germany. egrabhorn@uke.de
Key Words Donor-specific antibodies; Graft rejection; Liver transplantation; Fluoroimmunoassay; Pediatrics; Graft dysfunction; Fibrosis
Core Tip This was a retrospective study to evaluate the impact of donor-specific antibodies (DSAs) on graft survival with pediatric liver transplantation. Graft fibrosis and graft loss was significantly higher in patients with DSAs. Screening for DSAs should be included in follow-ups to avoid delayed identification of patients at risk of graft loss (rejection), and may be even more relevant for patients with early histological signs of possible allograft dysfunction (fibrosis). Moreover, patients with DSAs may be poor candidates for reduction of initial immunosuppression or even weaning.
Publish Date 2021-06-23 01:49
Citation Schotters FL, Beime J, Briem-Richter A, Binder T, Herden U, Grabhorn EF. Impact of donor-specific antibodies on long-term graft survival with pediatric liver transplantation. World J Hepatol 2021; 13(6): 673-685
URL https://www.wjgnet.com/1948-5182/full/v13/i6/673.htm
DOI https://dx.doi.org/10.4254/wjh.v13.i6.673
Full Article (PDF) WJH-13-673.pdf
Full Article (Word) WJH-13-673.docx
STROBE Statement 61431-STROBE-Statement-revision.pdf
Manuscript File 61431_Auto_Edited-JPY.docx
Answering Reviewers 61431-Answering reviewers.pdf
Audio Core Tip 61431-Audio core tip.m4a
Biostatistics Review Certificate 61431-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 61431-Conflict-of-interest statement.pdf
Copyright License Agreement 61431-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 61431-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 61431-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 61431-Language certificate.pdf
Peer-review Report 61431-Peer-review(s).pdf
Scientific Misconduct Check 61431-Bing-Liu M-1.png
Scientific Misconduct Check 61431-Scientific misconduct check.pdf
Scientific Editor Work List 61431-Scientific editor work list.pdf