Publication Name	World Journal of Clinical Cases
Manuscript ID	61547
Country	Germany

Received	2021-02-19 11:45
Peer-Review Started	2021-02-19 11:51
To Make the First Decision
Return for Revision	2021-03-25 04:21
Revised	2021-04-06 19:26
Second Decision	2021-07-14 03:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-14 05:52
Articles in Press	2021-07-14 05:52
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-19 05:51
Typeset the Manuscript	2021-08-17 02:21
Publish the Manuscript Online	2021-08-24 02:07

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Long-term survivor of metastatic squamous-cell head and neck carcinoma with occult primary after cetuximab-based chemotherapy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Christina Große-Thie, Claudia Maletzki, Christian Junghanss and Kathie Schmidt
ORCID	Author(s) ORCID Number Christina Große-Thie http://orcid.org/0000-0002-8128-0125 Claudia Maletzki http://orcid.org/0000-0002-8389-8439 Christian Junghanss http://orcid.org/0000-0003-4707-777X Kathie Schmidt http://orcid.org/0000-0002-1879-4596
Funding Agency and Grant Number
Corresponding Author	Kathie Schmidt, MD, Medical Assistant, Department of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, Rostock 18057, Germany. kathie.schmidt@med.uni-rostock.de
Key Words	Squamous cell carcinoma of the head and neck; Cancer of unknown primary; Long-term survival; Cetuximab; Metastases; Case report
Core Tip	A 42-year-old female patient suffered from metastatic squamous-cell head and neck cancer with occult primary with lymph node and bone metastases. She received palliative immune-chemotherapy with cetuximab, 5-fluorouracil, and platinum as first-line treatment and subsequent irradiation of further abdominal lymph node and bone metastases. Although survival rates are very poor in this setting the patient is still alive 10 years after treatment and in complete remission. Here, we present a rare case of long-term survival despite poor prognosis after palliative immunotherapy even before the era of immune checkpoint inhibitors.
Publish Date	2021-08-24 02:07
Citation	Große-Thie C, Maletzki C, Junghanss C, Schmidt K. Long-term survivor of metastatic squamous-cell head and neck carcinoma with occult primary after cetuximab-based chemotherapy: A case report. World J Clin Cases 2021; 9(24): 7092-7098
URL	https://www.wjgnet.com/2307-8960/full/v9/i24/7092.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i24.7092

Full Article (PDF)	WJCC-9-7092.pdf
Full Article (Word)	WJCC-9-7092.docx
CARE Checklist–2016	61547-CARE-Checklist–2016-revision.pdf
Manuscript File	61547-Review-Filipodia.docx
Answering Reviewers	61547-Answering reviewers.pdf
Audio Core Tip	61547-Audio core tip.wav
Conflict-of-Interest Disclosure Form	61547-Conflict-of-interest statement.pdf
Copyright License Agreement	61547-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	61547-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	61547-Language certificate.pdf
Peer-review Report	61547-Peer-review(s).pdf
Scientific Misconduct Check	61547-Bing-Wang JL-1.jpg
Scientific Misconduct Check	61547-Scientific misconduct check.pdf
Scientific Editor Work List	61547-Scientific editor work list.pdf