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Articles Published Processes
3/12/2021 10:29:06 AM | Browse: 567 | Download: 1439
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Received |
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2020-12-18 11:21 |
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Peer-Review Started |
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2020-12-18 11:22 |
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First Decision by Editorial Office Director |
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2021-01-11 04:22 |
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Return for Revision |
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2021-01-11 04:22 |
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Revised |
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2021-01-20 15:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2021-02-25 06:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2021-03-08 22:23 |
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Articles in Press |
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2021-03-08 22:23 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-11 03:53 |
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Publish the Manuscript Online |
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2021-03-12 10:29 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Minireviews |
| Article Title |
Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Christof Ernst Berberich, Jérôme Josse, Frédéric Laurent and Tristan Ferry |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Christof Ernst Berberich, MSc, PhD, Lecturer, Senior Scientist, Department of Medical Training, Heraeus Medical GmbH, Philipp-Reis-Str. 8/11, Wehrheim 612173, Hessen, Germany. christof.berberich@heraeus.com |
| Key Words |
Prosthetic joint infection; Antibiotic-loaded bone cement; Single low dose antibiotic-loaded bone cement; Dual high dose antibiotic-loaded bone cement; Antibiotic prophylaxis; Risk-for-infection patients |
| Core Tip |
The objective of an effective antibiotic prophylaxis in arthroplasty may be best achieved through the combination of a systemic and local application route via antibiotic-loaded bone cement. Based on the observation of strong synergistic effects in antibiotic elution and antimicrobial efficacy of dual antibiotic-loaded bone cements, the hypothesis of a clinically more meaningful prophylaxis has been tested against gentamicin-only containing bone cements. Evidence is provided that this easy-to-apply strategy might be successful, if important comorbidities or procedure-related factors predispose patients to higher infection risks than usual. |
| Publish Date |
2021-03-12 10:29 |
| Citation |
Berberich CE, Josse J, Laurent F, Ferry T. Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence. World J Orthop 2021; 12(3): 119-128 |
| URL |
https://www.wjgnet.com/2218-5836/full/v12/i3/119.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v12.i3.119 |
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