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Articles Published Processes
4/16/2021 10:13:42 AM | Browse: 407 | Download: 728
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Received |
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2021-01-05 22:40 |
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Peer-Review Started |
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2021-01-05 22:42 |
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To Make the First Decision |
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Return for Revision |
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2021-01-25 03:06 |
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Revised |
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2021-02-11 22:01 |
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Second Decision |
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2021-03-17 04:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-03-22 18:31 |
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Articles in Press |
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2021-03-22 18:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-29 01:25 |
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Publish the Manuscript Online |
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2021-04-16 10:13 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Bile acid indices as biomarkers for liver diseases I: Diagnostic markers
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jawaher Abdullah Alamoudi, Wenkuan Li, Nagsen Gautam, Marco Olivera, Jane Meza, Sandeep Mukherjee and Yazen Alnouti |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of Nebraska Medical Center-Clinical Research Center and Great Plains Health Research Consortium |
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| Society of American Gastrointestinal and Endoscopic Surgeons |
36-5360-2186-001 |
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| Corresponding Author |
Yazen Alnouti, PhD, Professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, 557 S 42nd Street, Omaha, NE 68198, United States. yalnouti@unmc.edu |
| Key Words |
Hepatobiliary diseases; Bile acids; Bile acid indices; Diagnosis; Biomarker; Liver diseases |
| Core Tip |
We have developed the concept of “Bile acids (BA) indices” based on the detailed quantitative analysis of the urinary BA profile in patients with cholestatic liver diseases. We demonstrated the use of BA indices as diagnostic biomarkers for cholestatic liver diseases. BA indices had much lower inter- and intra-individual variability compared to absolute concentrations of the total and individual BA. In addition, BA indices demonstrated high area under the receiver operating characteristic curves, and changes of BA indices were associated with the risk of having a liver disease as determined by the logistic regression analysis. |
| Publish Date |
2021-04-16 10:13 |
| Citation |
Alamoudi JA, Li W, Gautam N, Olivera M, Meza J, Mukherjee S, Alnouti Y. Bile acid indices as biomarkers for liver diseases: Diagnostic markers. World J Hepatol 2021; 13(4): 433-455 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i4/433.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i4.433 |
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