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Articles Published Processes
8/24/2021 2:07:00 AM | Browse: 295 | Download: 680
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Received |
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2021-02-21 11:28 |
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Peer-Review Started |
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2021-02-21 11:28 |
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To Make the First Decision |
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Return for Revision |
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2021-05-06 18:36 |
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Revised |
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2021-05-23 09:45 |
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Second Decision |
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2021-06-07 12:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-06-07 13:15 |
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Articles in Press |
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2021-06-07 13:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-16 07:25 |
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Typeset the Manuscript |
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2021-08-16 15:49 |
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Publish the Manuscript Online |
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2021-08-24 02:07 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Case Report |
| Article Title |
New mechanism of partial duplication and deletion of chromosome 8: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan Jiang, Shuang Tang, Fang He, Jue-Xin Yuan and Zhu Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shuang Tang, MBBS, Attending Doctor, Office of Prenatal Diagnosis, Mianyang People's Hospital, No. 10-12 West Jiannan Road, Fuchen District, Mianyang 621000, Sichuan Province, China. 154179285@qq.com |
| Key Words |
Chromosome 8; Spontaneous mutation; Mitosis; Non-invasive prenatal testing; Case report |
| Core Tip |
The mechanism of partial deletion/duplication at the end of chromosome 8 involves two prevailing theories: Parental chromosome 8 inversion producing unbalanced gametes, and recombination hot spot of chromosome 8p. Although the recombination hot spot of chromosome 8q occurring during mitosis is rarely reported, it was confirmed in the present case. Non-invasive prenatal testing (NIPT) for copy number variation has been used, but 40% or less mosaic abnormalities cannot be detected by NIPT. When chromosome 8 partial deletion/duplication occurs, in addition to the unbalanced gamete production caused by parental chromosome 8 inversion, attention should be paid to the mechanism of spontaneous recombination in meiosis or mitosis. |
| Publish Date |
2021-08-24 02:07 |
| Citation |
Jiang Y, Tang S, He F, Yuan JX, Zhang Z. New mechanism of partial duplication and deletion of chromosome 8: A case report. World J Clin Cases 2021; 9(24): 7139-7145 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i24/7139.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i24.7139 |
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